catalog number :
MBS200148
products full name :
Maspin antibody (clone AT2N6)
products short name :
Maspin
products name syn :
Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5; Serpin B5; Protease inhibitor 5; SERPINB5; PI5; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5 Serine (or cysteine) peptidase inhibitor; clade B; member 5; Ovalbumin; PI-5; Serpin peptidase inhibitor; Serpin peptidase inhibitor; clade B (ovalbumin); member 5; SERPINB5; Spi5; Spi7.
other names :
serpin B5; Serpin B5; serpin B5; PI-5; peptidase inhibitor 5; protease inhibitor 5 (maspin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 5; serpin peptidase inhibitor, clade B (ovalbumin), member 5; Maspin; Peptidase inhibitor 5; PI-5
other gene names :
SERPINB5; SERPINB5; PI5; maspin; PI5; PI-5
uniprot entry name :
SPB5_HUMAN
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunofluorescence (IF)
app notes :
The antibody has been tested by ELISA, Western blot analysis and Immunofluorescence analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.
other info1 :
Antigen Species: Human. Clone: Anti-human Maspin mAb, clone AT2N6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Maspin protein. Immunogen: Recombinant Maspin (1-375aa) purified from E Coli
products categories :
Development
products description :
Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas.
products references :
Lockett J. et al., (2006) J Cell Biochem 97(4):651-660 Khalkhali Ellis Z. et al., (2006) Clin Cancer Res 12(24):7279-7283
ncbi gb acc num :
NM_002639.4
ncbi mol weight :
25,763 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!Direct P53 Effectors Pathway 137939!!MicroRNAs In Cancer Pathway 852705!!MicroRNAs In Cancer Pathway 852928!!P53 Signaling Pathway 83055!!P53 Signaling Pathway 465