catalog number :
MBS200138
products full name :
PPIF (Cyclophilin F) antibody (clone AT1F5)
products short name :
PPIF
products name syn :
Peptidylprolyl isomerase F; CYP3; Cyp-D; PPIF; Peptidylprolyl isomerase F Cyclophilin 3; Cyclophilin D; Cyclophilin F; Cyp D; CYP3; CypD; hCyP3; Peptidylprolyl isomerase F (cyclophilin F); Peptidyl prolyl cis trans isomerase; mitochondral; Peptidylprolyl isomerase F; PPIase; Rotamase.
other names :
peptidyl-prolyl cis-trans isomerase F, mitochondrial; Peptidyl-prolyl cis-trans isomerase F, mitochondrial; peptidyl-prolyl cis-trans isomerase F, mitochondrial; PPIase F; cyclophilin 3; cyclophilin D; cyclophilin F; mitochondrial cyclophilin; peptidyl-prolyl cis-trans isomerase, mitochondrial; rotamase F; peptidylprolyl isomerase F; Cyclophilin D; CyP-D; CypD; Cyclophilin F; Mitochondrial cyclophilin; CyP-M; Rotamase F
products gene name :
PPIF
other gene names :
PPIF; PPIF; CYP3; CypD; CyP-M; Cyp-D; CYP3; PPIase F; CyP-D; CypD; CyP-M
uniprot entry name :
PPIF_HUMAN
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
app notes :
The antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:500~1:1,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:500 and Immunohistochemistry is 1:50.
other info1 :
Antigen Species: Human. Clone: Anti-human PPIF mAb, clone AT1F5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPIF protein. Immunogen: Recombinant human PPIF (30-207aa) purified from E Coli
products categories :
Enzymes & Proteases
products description :
Cyclophilin F (also known as Peptidylprolyl isomerase F, PPIF) is a member of peptidyl-prolyl cis-transisomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
products references :
Bowles kR, et al., (2000) Genomics 67(2):109-127 Bergsma DJ, et al., (1991) J Biol Chem 266(34):23204-23214
ncbi gb acc num :
NM_005729.3
ncbi mol weight :
16,541 Da
ncbi pathways :
Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!Huntington's Disease Pathway 83100!!Huntington's Disease Pathway 512!!Parkinson's Disease Pathway 83098!!Toxoplasmosis Pathway 169642!!Toxoplasmosis Pathway 169493!!CGMP-PKG Signaling Pathway 983748!!CGMP-PKG Signaling Pathway 985584
ncbi summary :
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]