This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
RBP4 antibody (clone AT2B4)
catalog :
MBS200135
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AT2B4
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, enzyme immunoassay
product information
catalog number :
MBS200135
products type :
Antibody
products full name :
RBP4 antibody (clone AT2B4)
products short name :
RBP4
products name syn :
RBP4; Retinol binding protein 4; Retinol binding protein 4 Plasma retinol binding protein 4; prbp; PRO2222; Retinol binding protein 4 interstitial; Retinol binding protein 4 plasma
other names :
retinol-binding protein 4; Retinol-binding protein 4; retinol-binding protein 4; PRBP; plasma retinol-binding protein; retinol-binding protein 4, interstitial; retinol binding protein 4, plasma; Plasma retinol-binding protein; PRBP; RBP
products gene name :
RBP4
other gene names :
RBP4; RBP4; RDCCAS; PRBP; RBP
uniprot entry name :
RET4_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
AT2B4
host :
Mouse
reactivity :
Human
sequence length :
201
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate), Immunohistochemistry (IHC)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1000. Recommended starting dilution is 1:500.
other info1 :
Antigen Species: Human. Clone: Anti-human RBP4 mAb, clone AT2B4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human RBP4 protein. Immunogen: Recombinant human RBP4 (19-201aa) purified from E Coli
products categories :
Metabolism
products description :
Retinol binding protein 4(RBP4) belongs to the lipocalin family and is the specific carrier for retinol in the blood. This protein was found to be expressed and secreted by adipose tissue, and was strongly associated with insulin resistance. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli.
products references :
Tan Bk, et al., (2007) J Clin Endocrinol Metab 92(7):2590-2597 Yao-Borengasser A, et al., (2007) J Clin Endocrinol Metab 92(7):2430-2432
ncbi gi num :
55743122
ncbi acc num :
NP_006735
ncbi gb acc num :
NM_006744.3
ncbi mol weight :
23,010 Da
ncbi pathways :
Disease Pathway 530764!!Diseases Associated With Visual Transduction Pathway 771581!!Retinoid Cycle Disease Events Pathway 771582!!Retinoid Metabolism And Transport Pathway 187208!!SREBP Signalling Pathway 219802!!Signal Transduction Pathway 477114!!The Canonical Retinoid Cycle In Rods (twilight Vision) Pathway 771585!!Visual Phototransduction Pathway 771584!!Vitamin A And Carotenoid Metabolism Pathway 198785!!Retinoate Biosynthesis I Pathway 545452
ncbi summary :
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq, Jul 2008]
size :
0.05 ml
price :
240 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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