Monoclonal Antibody to Connective Tissue Growth Factor (CTGF) | MyBioSource MBS2001321 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Monoclonal Antibody to Connective Tissue Growth Factor (CTGF)

catalog :

MBS2001321

quantity :

0.01 mg

price :

95 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

[4-2#]

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

MyBioSource product webpage

image

image 1 :

Western Blot: Sample: Recombinant CTGF, Human.

product information

catalog number :

MBS2001321

products type :

Antibody

products full name :

Monoclonal Antibody to Connective Tissue Growth Factor (CTGF)

products short name :

[Connective Tissue Growth Factor (CTGF)]

other names :

[connective tissue growth factor; Connective tissue growth factor; connective tissue growth factor; connective tissue growth factor; CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8]

products gene name :

[CTGF]

other gene names :

[CTGF; CTGF; CCN2; NOV2; HCS24; IGFBP8; CCN2; HCS24; IGFBP8; IBP-8; IGF-binding protein 8; IGFBP-8]

clonality :

Monoclonal

isotype :

IgG2b Kappa

clone :

[4-2#]

host :

Mouse

reactivity :

Human

specificity :

The antibody is a Mouse monoclonal antibody raised against CTGF. It has been selected for its ability to recognize CTGF in immunohistochemical staining and western blotting.

purity :

Protein A/G Affinity Chromatography

form :

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol

concentration :

500µg/mL

storage stability :

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

tested application :

WB; IHC; ICC; IP.

app notes :

Western blotting: 0.5-5µg/mL. Immunohistochemistry: 5-30µg/mL. Immunocytochemistry: 5-30µg/mL. Optimal working dilutions must be determined by end user

image1 heading :

Western Blot (WB)

other info1 :

Source: Monoclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant CTGF (Leu80~Leu200) expressed in E.coli

other info2 :

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2034969

ncbi gi num :

4503123

ncbi acc num :

NP_001892.1

ncbi gb acc num :

NM_001901.2

uniprot acc num :

P29279

ncbi mol weight :

35,205 Da

ncbi pathways :

Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); TGF-beta Receptor Signaling Pathway (138024)

ncbi summary :

The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009]

uniprot summary :

CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell adhesion; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 6q23.2. Cellular Component: cell cortex; cis-Golgi network; cytosol; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bound organelle; perinuclear region of cytoplasm; plasma membrane; proteinaceous extracellular matrix. Molecular Function: fibronectin binding; growth factor activity; heparin binding; insulin-like growth factor binding; integrin binding; protein binding; protein C-terminus binding. Biological Process: aging; angiogenesis; cartilage condensation; cell adhesion; cell differentiation; cell migration; cell-cell signaling; cell-matrix adhesion; epidermis development; fibroblast growth factor receptor signaling pathway; integrin-mediated signaling pathway; lung development; ossification; positive regulation of cell activation; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of JNK cascade; positive regulation of stress fiber formation; regulation of cell growth; regulation of chondrocyte differentiation; regulation of lipid metabolic process; response to amino acid; response to anoxia; response to estradiol; response to glucose stimulus; response to mineralocorticoid stimulus; response to peptide hormone; response to wounding; tissue homeostasis; transcription initiation from RNA polymerase II promoter

size1 :

0.01 mg

price1 :

95 USD

size2 :

0.02 mg

price2 :

105

size3 :

0.05 mg

price3 :

130

size4 :

0.1 mg

price4 :

160

size5 :

0.2 mg

price5 :

200

size6 :

1 mg

price6 :

440

more info or order :

MyBioSource product webpage