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company name :
MyBioSource
product type :
antibody
product name :
14-3-3 tau antibody (clone AT1A1)
catalog :
MBS200131
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AT1A1
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS200131
products type :
Antibody
products full name :
14-3-3 tau antibody (clone AT1A1)
products short name :
14-3-3 tau
products name syn :
YWHAQ; 1C5; HS1; 14-3-3 tau; Tyrosine 3/tryptophan 5 -monooxygenase activation protein; theta polypeptide; tyrosine 3-monooxygenase/ tryptophan 5-monooxygenase activation protein; theta polypeptide 14 3 3 protein T cell; 14 3 3 protein tau; 14 3 3 protein theta; 14 3 3 tau; 14 3 3 theta; KCIP1; Protein HS1; Protein kinase C inhibitor protein 1; tyr3/trp5 monooxygenase activation protein; theta; Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein; theta polypeptide.
other names :
14-3-3 protein theta; 14-3-3 protein theta; 14-3-3 protein theta; 14-3-3 protein T-cell; 14-3-3 protein tau; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta; 14-3-3 protein T-cell; 14-3-3 protein tau; Protein HS1
products gene name :
14-3-3 tau
other gene names :
YWHAQ; YWHAQ; 1C5; HS1; 14-3-3
uniprot entry name :
1433T_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
AT1A1
host :
Mouse
reactivity :
Human
sequence length :
245
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000.
other info1 :
Antigen Species: Human. Clone: Anti-human 14-3-3 tau mAb, clone AT1A1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human 14-3-3 tau protein. Immunogen: Recombinant human 14-3-3 tau (1-245aa) purified from E Coli
products categories :
Signal Transduction
products description :
The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms,beta, gamma,epsilon, sigma, zeta, tau andtau that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis.
products references :
Liu YC, et al., (1996) J Biol Chem 271:14591-14595 Xiao B, et al., (1995) Nature 376:188-191
ncbi gi num :
5803227
ncbi acc num :
NP_006817
ncbi gb acc num :
NM_006826.3
ncbi mol weight :
27,764 Da
ncbi pathways :
Activation Of BAD And Translocation To Mitochondria Pathway 105659!!Activation Of BH3-only Proteins Pathway 105658!!Alpha6-Beta4 Integrin Signaling Pathway 198807!!Apoptosis Pathway 105648!!Calcium Regulation In The Cardiac Cell Pathway 198906!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054!!Cell Cycle Pathway 463!!Class I PI3K Signaling Events Mediated By Akt Pathway 138020!!Epstein-Barr Virus Infection Pathway 585562
ncbi summary :
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq, Jul 2008]
size :
0.05 ml
price :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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