catalog number :
MBS200130
products full name :
FABP7 antibody (clone AT1D1)
products short name :
FABP7
products name syn :
Fatty acid binding protein 7; FABP7; Fatty acid binding protein 7 B FABP; BFABP; BLBP; Brain lipid binding protein; DKFZp547J2313; FABP 7; FABPB; Fatty acid binding protein 7 brain; Fatty acid binding protein brain; OTTHuMP00000017119; Mammary derived growth inhibitor related; MRG.
other names :
fatty acid-binding protein, brain; Fatty acid-binding protein, brain; fatty acid-binding protein, brain; Hypothetical protein DKFZp547J2313; brain lipid binding protein; brain lipid-binding protein; brain-type fatty acid-binding protein; fatty acid-binding protein 7; mammary-derived growth inhibitor related; mammary-derived growth inhibitor-related; fatty acid binding protein 7, brain; Brain lipid-binding protein; BLBP; Brain-type fatty acid-binding protein; B-FABP; Fatty acid-binding protein 7; Mammary-derived growth inhibitor related
products gene name :
FABP7
other gene names :
FABP7; FABP7; MRG; BLBP; FABPB; B-FABP; LTR2-FABP7; BLBP; FABPB; MRG; BLBP; B-FABP
uniprot entry name :
FABP7_HUMAN
reactivity :
Human, Mouse
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Tissue)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000 ~ 2000. Recommended starting dilution is 1:1000
other info1 :
Antigen Species: Human. Clone: Anti-human FABP7 mAb, clone AT1D1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FABP7 protein. Immunogen: Recombinant human FABP7 (1-132aa) purified from E Coli
products categories :
Enzymes & Proteases
products description :
FABP7 (Fatty acid binding protein 7) is also known as brain fatty acid-binding protein (B-FABP) and is a member of fatty acid-binding proteins (FABPs) which are a family of small, highly conserved, cytoplasmic proteins to bind long-chain fatty acids and other hydrophobic ligands. FABP7 is expressed in radial glia by the activation of Notch receptors and binds DHA with the highest affinity among all of FABPs.
products references :
Borchers T, et al., (1997) Prostaglandins Leukot. Essent. Fatty Acids. 57(1):77-84 Liu Rz, et al., (2003) Eur J Biochem. 270(4):715-25
ncbi gb acc num :
NM_001446.3
ncbi mol weight :
18,829 Da
ncbi pathways :
PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450)
ncbi summary :
The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
uniprot summary :
FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Lipid-binding; Cell development/differentiation; Cell cycle regulation. Chromosomal Location of Human Ortholog: 6q22-q23. Cellular Component: cell projection; cell soma; cytoplasm; nucleus. Molecular Function: transporter activity; lipid binding. Biological Process: negative regulation of cell proliferation; nervous system development; epithelial cell proliferation; neurogenesis; prepulse inhibition; transport; cell proliferation in forebrain