antibody

Biotin-Linked Antibody to C Reactive Protein (CRP)

MBS2001260

0.1 mg

205 USD

monoclonal

mouse

biotin

[7#]

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

Antibody

Biotin-Linked Antibody to C Reactive Protein (CRP)

[C Reactive Protein (CRP)]

[C-reactive protein; C-reactive protein; C-reactive protein; pentraxin 1; C-reactive protein, pentraxin-related]

[CRP]

[CRP; CRP; PTX1; PTX1]

CRP_HUMAN

Monoclonal

IgG2b Kappa

[7#]

Mouse

Porcine (Pig)

Protein A/G Affinity Chromatography

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

500ug/mL

Storage: Avoid repeated freeze/thaw cycles. Store at 4°C for frequent use. Aliquot and store at -20°C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition.

WB; IHC; ICC; IP

Western blotting: 0.5-5ug/mL. Immunohistochemistry: 5-30ug/mL. Immunocytochemistry: 5-30ug/mL. Optimal working dilutions must be determined by end user

Western Blot (WB)

Source: Monoclonal antibody preparation. Label: Biotin. Traits: Liquid. Immunogen: Recombinant CRP (Gln20~Pro222)expressed in E.coli

Unconjugated Antibody: The unconjugated antibody version of this item is also available as catalog #MBS2001320

Biotin Antibody

55770842

NP_000558.2

NM_000567.2

P02741

Classical Antibody-mediated Complement Activation Pathway (106409); Complement Cascade Pathway (106405); Creation Of C4 And C2 Activators Pathway (106407); IL6-mediated Signaling Events Pathway (137932); Immune System Pathway (106386); Initial Triggering Of Complement Pathway (106406); Innate Immune System Pathway (106387); Selenium Pathway (198825)

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. [provided by RefSeq, Sep 2009]

CRP: Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Belongs to the pentaxin family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1q23.2. Cellular Component: extracellular space; growth cone; extracellular region; filopodium. Molecular Function: choline binding; protein binding; protein homodimerization activity; low-density lipoprotein receptor binding; complement component C1q binding; cholesterol binding; low-density lipoprotein binding; virion binding; calcium ion binding. Biological Process: protein polymerization; defense response to Gram-positive bacterium; response to ethanol; wound healing; negative regulation of vasodilation; positive regulation of superoxide release; response to lead ion; response to hypoxia; acute-phase response; opsonization; inflammatory response; complement activation, classical pathway; aging

0.1 mg

205 USD

0.2 mg

270

1 mg

630