This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
NRG1(HRG-beta3) antibody (clone k1G13)
catalog :
MBS200114
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
k1G13
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
product information
catalog number :
MBS200114
products type :
Antibody
products full name :
NRG1(HRG-beta3) antibody (clone k1G13)
products short name :
NRG1
products name syn :
neuregulin 1 isoform HRG-beta3; neuregulin 1; HRG; NDF; GGF
other names :
pro-neuregulin-1, membrane-bound isoform isoform HRG-beta3; Pro-neuregulin-1, membrane-bound isoform; pro-neuregulin-1, membrane-bound isoform; glial growth factor; heregulin, alpha (45kD, ERBB2 p185-activator); neu differentiation factor; pro-NRG1; sensory and motor neuron derived factor; neuregulin 1; Acetylcholine receptor-inducing activity; ARIA; Breast cancer cell differentiation factor p45; Glial growth factor; Heregulin; HRG; Neu differentiation factor; Sensory and motor neuron-derived factor
products gene name :
NRG1
other gene names :
NRG1; NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2; GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG
uniprot entry name :
NRG1_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
k1G13
host :
Mouse
reactivity :
Human
sequence length :
241
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.
other info1 :
Antigen Species: Human. Clone: Anti-human NRG1 mAb, clone k1G13, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NRG1 protein. Immunogen: Recombinant human NRG1 isoform HRG-beta3 (20-241aa) purified from E Coli
products categories :
Development
products description :
Neuregulin1 (NRG1) is one of four proteins in the neuregulin family that act on the Epidermal growth factor receptor (EGFR) family of receptors. NRG1 was originally identified as a 44 kDa glycoprotein that interacts with the ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. In many brain areas, NRG1 is expressed at synaptic regions and its processing can be regulated by neuronal activity. This variant (HRG-beta3) of NRG1, along with HRG-alpha, beta1 and beta2 variants, was identified in various normal tissues and cancer cell lines.
products references :
Talmage D.A, et al., (2008) Novartis Found Symp. 289:74-93 Li B, et al., (2007) Neuron. 54(4):583-597 Law A.J, et al., (2006) Proc Natl Acad Sci U S A. 103(17):6747-6752
ncbi gi num :
116006959
ncbi acc num :
NP_039252
ncbi gb acc num :
NM_013958.3
ncbi mol weight :
46,226 Da
ncbi pathways :
Adaptive Immune System Pathway 366160!!Cardiac Progenitor Differentiation Pathway 712094!!Constitutive PI3K/AKT Signaling In Cancer Pathway 685535!!DAP12 Interactions Pathway 685549!!DAP12 Signaling Pathway 685550!!Disease Pathway 530764!!Downregulation Of ERBB2:ERBB3 Signaling Pathway 530740!!Downstream Signal Transduction Pathway 106385!!Downstream Signaling Events Of B Cell Receptor (BCR) Pathway 576250!!Downstream Signaling Of Activated FGFR Pathway 160957
ncbi summary :
The protein encoded by this gene is a membrane glycoprotein that that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). [provided by RefSeq, Jun 2014]
size :
0.05 ml
price :
240 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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