FABP1 antibody (clone 2G4) | MyBioSource MBS200109 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

FABP1 antibody (clone 2G4)

catalog :

MBS200109

quantity :

0.05 mL

price :

240 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2G4

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS200109

products type :

Antibody

products full name :

FABP1 antibody (clone 2G4)

products short name :

FABP1

products name syn :

Fatty acid-binding protein; liver; FABPL; L-FABP; FABP1; Fatty acid binding protein 1; fatty acid binding protein 1 liver

other names :

fatty acid-binding protein, liver; Fatty acid-binding protein, liver; fatty acid-binding protein, liver; fatty acid-binding protein 1; liver-type fatty acid-binding protein; fatty acid binding protein 1, liver; Fatty acid-binding protein 1; Liver-type fatty acid-binding protein; L-FABP

products gene name :

FABP1

other gene names :

FABP1; FABP1; FABPL; L-FABP; FABPL; L-FABP

uniprot entry name :

FABPL_HUMAN

clonality :

Monoclonal

isotype :

IgG1, k

clone :

2G4

host :

Mouse

reactivity :

Human

sequence length :

127

purity :

By protein-G affinity chromatography

form :

Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

concentration :

1mg/ml

storage stability :

Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.

tested application :

ELISA (EIA), Western Blot (WB) (Cell lysate), Immunohistochemistry (IHC)

app notes :

The antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:1,000 ~ 1:2,000 and immunohistochemistry analysis is 1:100~300. Recommended starting dilution for Western blot is 1:1,000 and Immunohistochemistry is 1:100.

other info1 :

Antigen Species: Human. Clone: Anti-human FABP1 mAb, clone 2G4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human FABP1 protein. Immunogen: Recombinant human FABP1 (1-127aa) purified from E Coli

products categories :

Enzymes & Proteases

products description :

FABP1 (Fatty acid binding protein1) encodes the fatty acid binding protein found in liver. FABP1 is composed of ten antiparallelbeta strands that form a barrel with a bigger binding pocket than the other FABPs allowing it to accommodate two fatty acid. This protein binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm; it may be involved in intracellular lipid transport and metabolism.

products references :

Atshaves BP, et al: (2004) Mol Cell Biochem. 259(1-2), 115-29 Nakamura T, et al: (2005) Diabestes Care. 28(11), 2728-32

ncbi gi num :

4557577

ncbi acc num :

NP_001434

ncbi gb acc num :

NM_001443.2

ncbi mol weight :

14,208 Da

ncbi pathways :

Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPAR Signaling Pathway (83042); PPAR Signaling Pathway (450); PPARA Activates Gene Expression Pathway (530749); Regulation Of Lipid Metabolism By Peroxisome Proliferator-activated Receptor Alpha (PPARalpha) Pathway (119544); Selenium Metabolism And Selenoproteins Pathway (198846)

ncbi summary :

This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]

uniprot summary :

FABP1: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Protein type: Lipid-binding. Chromosomal Location of Human Ortholog: 2p11. Cellular Component: nucleoplasm; peroxisomal matrix; apical cortex; cytosol. Molecular Function: antioxidant activity; bile acid binding; phospholipid binding; long-chain fatty acid transporter activity; drug binding; chromatin binding; fatty acid binding. Biological Process: long-chain fatty acid transport; positive regulation of cell proliferation; positive regulation of hydrolase activity; negative regulation of caspase activity; cellular lipid metabolic process; positive regulation of fatty acid beta-oxidation; intestinal absorption; negative regulation of apoptosis

size1 :

0.05 mL

price1 :

240 USD

size2 :

0.1 mL

price2 :

315

more info or order :

MyBioSource product webpage