UBE2L6 antibody (clone k1H3) | MyBioSource MBS200108 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

UBE2L6 antibody (clone k1H3)

catalog :

MBS200108

quantity :

0.05 ml

price :

240 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

k1H3

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS200108

products type :

Antibody

products full name :

UBE2L6 antibody (clone k1H3)

products short name :

UBE2L6

products name syn :

uBCH8; RIG-B; ubiquitin conjugating enzyme E2L 6; uBE2L6; ubiquitin conjugating enzyme E2L 6 MGC40331; Retinoic acid induced gene B protein; RIG B; uBCH 8; ubiquitin carrier protein; ubiquitin carrier protein L6; ubiquitin protein ligase; ubiquitin protein ligase L6; ubiquitin/ISG15 conjugating enzyme E2 L6.

other names :

ubiquitin/ISG15-conjugating enzyme E2 L6 isoform 1; Ubiquitin/ISG15-conjugating enzyme E2 L6; ubiquitin/ISG15-conjugating enzyme E2 L6; retinoic acid induced gene B protein; retinoic acid-induced gene B protein; ubiquitin carrier protein L6; ubiquitin-protein ligase L6; ubiquitin-conjugating enzyme E2L 6; Retinoic acid-induced gene B protein; RIG-B; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6

products gene name :

UBE2L6

other gene names :

UBE2L6; UBE2L6; RIG-B; UBCH8; UBCH8; RIG-B

uniprot entry name :

UB2L6_HUMAN

clonality :

Monoclonal

isotype :

IgG2b, k

clone :

k1H3

host :

Mouse

reactivity :

Human

sequence length :

153

purity :

By protein-G affinity chromatography

form :

Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

concentration :

1mg/ml

storage stability :

Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.

tested application :

ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)

app notes :

The antibody has been tested by ELISA, Western blot and immunohistochemistry analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot is 1:1,000~1:3,000 and immunohistochemistry analysis is 1:50~100. Recommended starting dilution for Western blot is 1:2,000 and Immunohistochemistry is 1:50.

other info1 :

Antigen Species: Human. Clone: Anti-human UBE2L6 mAb, clone k1H3, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human UBE2L6 protein. Immunogen: Recombinant human UBE2L6 (1-152aa) purified from E Coli

products categories :

Ubiquitination

products description :

Ubiquitin-conjugating enzyme E2L6 (UBE2L6), also known as UbcH8, is a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination of a protein substrate requires the concerted action of 3 classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin protein ligases. The E2 ubiquitin-conjugating enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene.

products references :

Ardley HC., et al. (2000) Cytogenet Cell Genet. 89(1-2):137-140 Movnihan TP., et al. (1999) J Biol Chem. 274(43):30963-30968 kumar S., et al. (1997) J Biol Chem. 272(21):13548-13554

ncbi gi num :

4759282

ncbi acc num :

NP_004214

ncbi gb acc num :

NM_004223.4

ncbi mol weight :

10,086 Da

ncbi pathways :

Adaptive Immune System Pathway 366160!!Antigen Processing: Ubiquitination Proteasome Degradation Pathway 366162!!Antiviral Mechanism By IFN-stimulated Genes Pathway 530760!!Class I MHC Mediated Antigen Processing Presentation Pathway 366161!!Cytokine Signaling In Immune System Pathway 366171!!ISG15 Antiviral Mechanism Pathway 530761!!Immune System Pathway 106386!!Innate Immune System Pathway 106387!!Interferon Signaling Pathway 187103!!Negative Regulators Of RIG-I/MDA5 Signaling Pathway 187102

ncbi summary :

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2011]

size :

0.05 ml

price :

240 USD

more info or order :

MyBioSource product webpage