catalog number :
MBS200093
products full name :
Calmodulin antibody (clone J4D8)
products short name :
Calmodulin
products name syn :
PHKD; CAMII; PHKD2; Calmodulin 2; CALM 2; Calmodulin2; CAM II; LP7057 protein; PHKD 2; Phosphorylase kinase delta; Calmodulin-2
other names :
calmodulin; Calmodulin; calmodulin; LP7057 protein; caM; phosphorylase kinase delta; prepro-calmodulin 2; calmodulin 2 (phosphorylase kinase, delta)
other gene names :
CALM2; CALM1; PHKD; CAMII; PHKD2; CALM; CAM; CAM1; CaM
uniprot entry name :
CALM_HUMAN
reactivity :
Human, Mouse
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.
other info1 :
Antigen Species: Human. Clone: Anti-human Calmodulin mAb, clone J4D8, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Calmodulin protein. Immunogen: Recombinant human Calmodulin (1-149aa) purified from E Coli
products categories :
Signal Transduction
products description :
Calmodulin has been known to act as an intracellular calcium sensor protein. When the intracellular Ca2+ concentration increases, calmodulin can bind up to four Ca2+, changing its conformation and regulating cellular functions such as activation or inhibition of a large number of enzymes, ion channels, and receptors.
products references :
Zhang M., et al. (1998). Biochem Cell Biol. 76(2-3):313-23 James.P., et al. (1995). Trend Biochem Sci. 20: 38-42
ncbi gb acc num :
NM_001743.4
ncbi mol weight :
16,838 Da
ncbi pathways :
Activation Of Ca-permeable Kainate Receptor Pathway 161046!!Activation Of CaMK IV Pathway 161042!!Activation Of Kainate Receptors Upon Glutamate Binding Pathway 161043!!Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway 161033!!Adaptive Immune System Pathway 366160!!Adrenergic Signaling In Cardiomyocytes Pathway 908257!!Adrenergic Signaling In Cardiomyocytes Pathway 909696!!Alcoholism Pathway 585563!!Alcoholism Pathway 587116!!Alzheimer's Disease Pathway 83097