product summary
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company name :
MyBioSource
product type :
antibody
product name :
Cyclophilin B antibody (clone k2E2)
catalog :
MBS200088
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
k2E2
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS200088
products type :
Antibody
products full name :
Cyclophilin B antibody (clone k2E2)
products short name :
Cyclophilin B
products name syn :
PPIB; Peptidylprolyl isomerase B; CYPB; SCYLP; CYP-S1: Cyclophilin-B; Cyclophilin B; 26- 216aa; AA553318; AI844835; Cphn 2; Cphn2; CyP 20b; AA408962; CYP S1; MGC14109; MGC2224; peptidyl prolyl cis trans isomerase B; Peptidyl prolyl cis trans isomerase B precursor; PPIase; Rotamase; S cyclophilin.
other names :
peptidyl-prolyl cis-trans isomerase B; Peptidyl-prolyl cis-trans isomerase B; peptidyl-prolyl cis-trans isomerase B; PPIase B; S-cyclophilin; cyclophilin-like protein; epididymis secretory protein Li 39; rotamase B; peptidylprolyl isomerase B (cyclophilin B); CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP
other gene names :
PPIB; PPIB; OI9; CYPB; SCYLP; CYP-S1; HEL-S-39; CYPB; PPIase B; SCYLP
uniprot entry name :
PPIB_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
k2E2
host :
Mouse
reactivity :
Human
sequence length :
216
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.
other info1 :
Antigen Species: Human. Clone: Anti-human Cyclophilin B mAb, clone k2E2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Cyclophilin B protein. Immunogen: Recombinant human Cyclophilin B (26-216aa) purified from E Coli
products categories :
Signal Transduction
products description :
Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Cyclophilin B is necessary for the prolactin-induced proliferation, cell growth, and the nuclear retrotransport of prolactin.
products references :
Watashi k, et al., (2005) Mol Cell 19(1):111-112 Yurchenko V, et al., (2001) Biochem Biophys Res Commun 288(4):786-788 E.Roydon P, et al., (1991) Proc Natl Acad Sci USA 88:1903-1907
ncbi gi num :
4758950
ncbi acc num :
NP_000933
ncbi gb acc num :
NM_000942.4
ncbi mol weight :
23,743 Da
ncbi pathways :
Collagen Biosynthesis And Modifying Enzymes Pathway 645289!!Collagen Formation Pathway 645288!!Extracellular Matrix Organization Pathway 576262!!Prolactin Signaling Pathway 672462!!Syndecan-1-mediated Signaling Events Pathway 138046
ncbi summary :
The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
size :
0.05 ml
price :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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