catalog number : 
MBS200086
products full name : 
CD29 antibody (clone k2D5)
products short name : 
CD29
products name syn : 
Integrin beta 1 isoform 1a(fibronectin receptor; beta polypeptide); integrin beta 1 (fibronectin receptor; beta polypeptide; antigen CD29 includes MDF2; MSK12); FNRB; MSK12; MDF2; GPIIA
other names : 
integrin beta-1 isoform 1A; Integrin beta-1; integrin beta-1; glycoprotein IIa; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; VLA-4 subunit beta; CD_antigen: CD29
products gene name : 
CD29
other gene names : 
ITGB1; ITGB1; CD29; FNRB; MDF2; VLAB; GPIIA; MSK12; VLA-BETA; FNRB; MDF2; MSK12; GPIIA
uniprot entry name : 
ITB1_HUMAN
purity : 
By protein-G affinity chromatography
form : 
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
storage stability : 
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application : 
ELISA (EIA), Western Blot (WB) (Cell lysate)
app notes : 
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1,000. Recommended starting dilution is 1:500.
other info1 : 
Antigen Species: Human.  Clone: Anti-human CD29 mAb, clone k2D5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CD29 protein.  Immunogen: Recombinant human CD29 (34-141aa) purified from E Coli
products categories : 
Immunology
products description : 
CD29, also known as Integrin beta 1, is the beta subunit found in the integrin families, forming a heterodimer integrin receptor through non-covalent bonding with various integrin alpha subunits. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. Interaction between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression.
products references : 
He L, et al., (2003) Blood 102(10):3652-3657 Arrequi C, et al., (2000) J cell Biol 149(6):1263-1274 Martin-padura I, et al., (1994) J Biol Chem 269:6124-6132
ncbi gb acc num : 
NM_002211.3
ncbi mol weight : 
88,884 Da
ncbi pathways : 
Adaptive Immune System Pathway  366160!!Angiopoietin Receptor Tie2-mediated Signaling Pathway  137917!!Arf6 Trafficking Events Pathway  137954!!Arrhythmogenic Right Ventricular Cardiomyopathy Pathway  672454!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway  117293!!Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway  116129!!Axon Guidance Pathway  83065!!Axon Guidance Pathway  476!!Axon Guidance Pathway  105688!!Bacterial Invasion Of Epithelial Cells Pathway  149807
ncbi summary : 
Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]