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company name :
MyBioSource
product type :
antibody
product name :
Hexokinase 1, 2 antibody (clone 1A7)
catalog :
MBS200075
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
1A7
reactivity :
human
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS200075
products type :
Antibody
products full name :
Hexokinase 1, 2 antibody (clone 1A7)
products short name :
Hexokinase 1
products name syn :
HK2; Hexokinase 2; EC 2.7.1.1; Hexokinase type II; HK II; Muscle form hexokinase; Hexokinase-2; hexokinase 2; HK1; Hexokinase 1; EC 2.7.1.1; Hexokinase type I; HK I; Brain form hexokinase; Hexokinase-1; BB404130; dea; Glycolytic enzyme; HEXOKIN; Hexokinase PI; Hexokinase type I; Hexokinase; tumor isozyme; Hexokinase-A; HK1 tb; Hk1-s; HK1-ta; HK1-tc; HKI; HXK1; mHk1-s.
other names :
hexokinase-2; Hexokinase-2; hexokinase-2; HK II; hexokinase type II; hexokinase-2, muscle; muscle form hexokinase; hexokinase 2; Hexokinase type II; HK II; Muscle form hexokinase
other gene names :
HK2; HK2; HKII; HXK2; HK II
uniprot entry name :
HXK2_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
1A7
host :
Mouse
reactivity :
Human
sequence length :
917
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate)
app notes :
The antibody recognizes all four isoforms of Hexokinase (1, 2) in recombinant protein. The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 3,000. Recommended starting dilution is 1:2,000.
other info1 :
Antigen Species: Human. Clone: Anti-human Hexokinase 2 mAb, clone 1A7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Hexokinase 2 protein. Immunogen: Recombinant human Hexokinase 2 (1-917aa) purified from E Coli
products categories :
Signal Transduction
products description :
Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes (types 1 to 4 hexokinases) have been identified. These enzymes are found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase 2 is found in the skeletal muscle and includes hydrophobic N-terminal sequence capable of targeting the hexokinase to mitochondria.
products references :
Furuta H, et al.,(1996) Genomics 36(1):206-209 Jon E, et al., (2003) J Exp Biology 206:2049-2057
ncbi gi num :
15553127
ncbi acc num :
NP_000180
ncbi gb acc num :
NM_000189.4
ncbi mol weight :
102,380 Da
ncbi pathways :
Amino Sugar And Nucleotide Sugar Metabolism Pathway 82979!!Amino Sugar And Nucleotide Sugar Metabolism Pathway 350!!Butirosin And Neomycin Biosynthesis Pathway 145809!!Butirosin And Neomycin Biosynthesis Pathway 145786!!Carbohydrate Digestion And Absorption Pathway 170720!!Carbohydrate Digestion And Absorption Pathway 170654!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Central Carbon Metabolism In Cancer Pathway 1059538!!Central Carbon Metabolism In Cancer Pathway 1084231
ncbi summary :
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]
size :
0.05 ml
price :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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