product summary
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company name :
MyBioSource
product type :
antibody
product name :
Interferon regulatory factor-3 antibody (clone 3F10)
catalog :
MBS200059
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3F10
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS200059
products type :
Antibody
products full name :
Interferon regulatory factor-3 antibody (clone 3F10)
products short name :
Interferon regulatory factor-3
products name syn :
IRF3; Interferon regulatory factor-3; IRF-3; Interferon regulatory factor 3; IRF 3.
other names :
interferon regulatory factor 3 isoform 1; Interferon regulatory factor 3; interferon regulatory factor 3; interferon regulatory factor 3
other gene names :
IRF3; IRF3; IRF-3
uniprot entry name :
IRF3_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
3F10
host :
Mouse
reactivity :
Human
sequence length :
427
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.01% Sodium Azide.
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate), Immunoprecipitation (IP), Immunofluorescence (IF)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1,000 ~ 2,000. Recommended starting dilution is 1:1,000.
other info1 :
Antigen Species: Human. Clone: Anti-human IRF-3 mAb, clone 3F10, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IRF-3 protein. Immunogen: Recombinant human IRF-3(108-166aa) purified from E Coli
products categories :
Hormones & Cytokines
products description :
Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection.
products references :
DeFilippis VR et al.,(2006) J Virol 80(2):1032-1037 Pietila TE et al.,(2007) J Immunol 178(1):253-261
ncbi gi num :
4504725
ncbi acc num :
NP_001562
ncbi gb acc num :
NM_001571.5
ncbi mol weight :
12,330 Da
ncbi pathways :
Activated TLR4 Signalling Pathway 106400!!Activation Of IRF3/IRF7 Mediated By TBK1/IKK Epsilon Pathway 187088!!Antiviral Mechanism By IFN-stimulated Genes Pathway 530760!!Apoptosis Pathway 198797!!Cytokine Signaling In Immune System Pathway 366171!!Cytosolic DNA-sensing Pathway 125137!!Cytosolic DNA-sensing Pathway 124833!!Cytosolic Sensors Of Pathogen-associated DNA Pathway 576255!!Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115
ncbi summary :
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
size :
0.05 ml
price :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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