product summary
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company name :
MyBioSource
product type :
antibody
product name :
BMP7 antibody (clone 4E7)
catalog :
MBS200028
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
4.00E+07
reactivity :
human, mouse, rat
application :
western blot, ELISA, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS200028
products type :
Antibody
products full name :
BMP7 antibody (clone 4E7)
products short name :
BMP7
products name syn :
Osteogenic protein1; OP-1; Bone morphogenetic protein 7 BMP 7; Eptotermin alfa; OP 1; OP1.
other names :
bone morphogenetic protein 7; Bone morphogenetic protein 7; bone morphogenetic protein 7; osteogenic protein 1; bone morphogenetic protein 7; Osteogenic protein 1; OP-1; INN: Eptotermin alfa
products gene name :
BMP7
other gene names :
BMP7; BMP7; OP-1; OP1; BMP-7; OP-1
uniprot entry name :
BMP7_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
4.00E+07
host :
Mouse
reactivity :
Human, Mouse, Rat
sequence length :
431
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate)
app notes :
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.
other info1 :
Antigen Species: Human. Clone: Anti-human BMP7 mAb, clone 4E7, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human BMP7 protein. Immunogen: Recombinant human BMP7 (293-431aa) purified from E Coli
products categories :
Hormones & Cytokines
products description :
BMP-7 (bone morphogenetic protein-7), also known as OP-1 (osteogenic protein-1), is a member of the transforming growth factorbeta(TGFbeta) superfamily. BMP-7 plays an essential role during ontogeny of the mammalian eye and kidney, also, is expressed in heart, lung, small intestine, limb bud and teeth. In addition, noggin, one of the soluble BMP antagonists, regulated the action of BMPs on mesenchymal precursor cells, partially through a feedback type of inhibition.
products references :
Gregory kE., et al. (2005) J. Biol, Chem. 280, 27970-27980. Sampath Tk., et al. (1990) J. Biol. Chem. 265, 13198-13205 Godin RE., et al. (1998) Development. 125, 3473-3482 Groppe J., et al. (2002) Nature. 420, 636-642
ncbi gi num :
4502427
ncbi acc num :
NP_001710
ncbi gb acc num :
NM_001719.2
ncbi mol weight :
49,313 Da
ncbi pathways :
ALK2 Signaling Events Pathway 137983!!BMP Receptor Signaling Pathway 137948!!BMP Signaling Pathway 1084755!!BMP Signaling Pathway 1108218!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Elastic Fibre Formation Pathway 730310!!Endochondral Ossification Pathway 198812!!Extracellular Matrix Organization Pathway 576262!!Hippo Signaling Pathway 749777
ncbi summary :
The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity. [provided by RefSeq, Jul 2008]
size :
0.05 ml
price :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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