C/EBP-Beta antibody (clone 47A1) | MyBioSource MBS200024 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

C/EBP-Beta antibody (clone 47A1)

catalog :

MBS200024

quantity :

0.05 ml

price :

240 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

47A1

reactivity :

human, mouse

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS200024

products type :

Antibody

products full name :

C/EBP-Beta antibody (clone 47A1)

products short name :

C/EBP-Beta

products name syn :

CEBPB(CCAAT/enhancer binding protein; beta); LAP; CRP2; TCF5; IL6DBP; NF-IL6; MGC32080; C/EBP-beta; CCAAT/enhancer binding protein (C/EBP) beta; NFIL6; liver-enriched transcriptional activator protein; nuclear factor of interleukin 6; interleukin 6-dependent DNA-binding protein

other names :

CCAAT/enhancer-binding protein beta isoform a; CCAAT/enhancer-binding protein beta; CCAAT/enhancer-binding protein beta; interleukin 6-dependent DNA-binding protein; nuclear factor NF-IL6; nuclear factor of interleukin 6; transcription factor 5; CCAAT/enhancer binding protein (C/EBP), beta; Liver activator protein; LAP; Liver-enriched inhibitory protein; LIP; Nuclear factor NF-IL6; Transcription factor 5; TCF-5

products gene name :

C/EBP-Beta

other gene names :

CEBPB; CEBPB; TCF5; IL6DBP; NF-IL6; C/EBP-beta; TCF5; C/EBP beta; LAP; LIP; TCF-5

uniprot entry name :

CEBPB_HUMAN

clonality :

Monoclonal

isotype :

IgG1, k

clone :

47A1

host :

Mouse

reactivity :

Human, Mouse

sequence length :

345

purity :

By protein-G affinity chromatography

form :

Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

concentration :

1mg/ml

storage stability :

Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.

tested application :

ELISA (EIA), Western Blot (WB) (Cell lysate)

app notes :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.

other info1 :

Antigen Species: Human. Clone: Anti-human C/EBP beta mAb, clone 47A1, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human C/EBP beta protein. Immunogen: Recombinant human C/EBP-beta (1-271 aa) purified from E Coli

products categories :

Signal Transduction

products description :

CCAAT/enhancer-binding proteins (C/EBPs) are a family of basic leucine zipper (bZIP) DNA binding proteins that play important roles in normal cellular differentiation and function in a variety of tissues. The C/EBP family is critical for innate immunity and inflammatory response, and consists of five core members: C/EBPalpha, C/EBPbeta, C/EBPdelta, C/EBPepsilon, and C/EBPgamma. Among these proteins, C/EBPbeta is usually highly expressed in liver, intestine, lung and adipose. C/EBPbeta has three isoforms, two activator, (LAP* and LAP) and a repressor (LIP). These isoforms are differentially translated from the same mRNA. The expression of these isoforms is developmentally and hormonally regulated.

products references :

Lekstrom-Himes J. et al. (1998) J Biol. Chem. 273, 28545-28548 Parkin SE. et al. (2002) J Biol. Chem; 277, 23563-23572 Su WC. et al. (2003) J Biol. Chem. 278, 51150-51158

ncbi gi num :

28872796

ncbi acc num :

NP_005185

ncbi gb acc num :

NM_005194.3

ncbi mol weight :

15,938 Da

ncbi pathways :

Adipogenesis Pathway 198832!!C-MYB Transcription Factor Network Pathway 138073!!Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Developmental Biology Pathway 477129!!Diurnally Regulated Genes With Circadian Orthologs Pathway 198813!!EGFR1 Signaling Pathway 198782!!FOXA1 Transcription Factor Network Pathway 137979!!FOXA2 And FOXA3 Transcription Factor Networks Pathway 137911!!IFN-gamma Pathway 138040

ncbi summary :

This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013]

size :

0.05 ml

price :

240 USD

more info or order :

MyBioSource product webpage