product summary
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company name :
MyBioSource
product type :
antibody
product name :
IRF-5 antibody (clone 10T1)
catalog :
MBS200023
quantity :
0.05 ml
price :
240 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
10T1
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation, enzyme immunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS200023
products type :
Antibody
products full name :
IRF-5 antibody (clone 10T1)
products short name :
IRF-5
products name syn :
interferon regulatory factor 5; irf5
other names :
Interferon regulatory factor 5; interferon regulatory factor 5; interferon regulatory factor 5
products gene name :
IRF-5
other gene names :
IRF5; IRF5; SLEB10; IRF-5
uniprot entry name :
IRF5_HUMAN
clonality :
Monoclonal
isotype :
IgG1, k
clone :
10T1
host :
Mouse
reactivity :
Human, Mouse
sequence length :
147
purity :
By protein-G affinity chromatography
form :
Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
concentration :
1mg/ml
storage stability :
Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.
tested application :
ELISA (EIA), Western Blot (WB) (Cell lysate), Immunoprecipitation (IP), Immunohistochemistry (IHC)
app notes :
The antibody has been tested by ELISA, Western blot, IP, and immunohistochemical analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 1:1,000. Recommended starting dilution is 1:1,000.
other info1 :
Antigen Species: Human. Clone: Anti-human IRF-5 mAb, clone 10T1, is derived from hybridization of mouse SP2/0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human IRF-5 protein. Immunogen: Recombinant human IRF-5 (176-240aa) purified from E Coli
products categories :
Hormones & Cytokines
products description :
Interferon regulatory factor 5(IRF-5) is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs(IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.
products references :
Mario B. et al. (2007) J. Virology 81(9):4473-4481. Ning S. et al. (2005) J. Virology 79:11671-11676. Mario B. et al. (2007) J. Virology 81(9):4473-4481
ncbi gi num :
4504727
ncbi acc num :
NP_002191
ncbi gb acc num :
NM_002200.3
ncbi mol weight :
17,020 Da
ncbi pathways :
Apoptosis Pathway 198797!!Cytokine Signaling In Immune System Pathway 366171!!Direct P53 Effectors Pathway 137939!!Immune System Pathway 106386!!Interferon Signaling Pathway 187103!!Interferon Alpha/beta Signaling Pathway 187104!!Interferon Gamma Signaling Pathway 187106!!Regulation Of Toll-like Receptor Signaling Pathway 920955!!Senescence And Autophagy Pathway 198780!!Toll-like Receptor Signaling Pathway 83076
ncbi summary :
This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. [provided by RefSeq, Mar 2010]
size :
0.05 ml
price :
240 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

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