Adiponectin antibody (clone 1G12) | MyBioSource MBS200018 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Adiponectin antibody (clone 1G12)

catalog :

MBS200018

quantity :

0.05 ml

price :

240 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1G12

reactivity :

human, mouse

application :

western blot, ELISA, enzyme immunoassay

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS200018

products type :

Antibody

products full name :

Adiponectin antibody (clone 1G12)

products short name :

Adiponectin

products name syn :

ADIPOQ; ACDC; ACRP30; APM1; GBP28; Adiponectin globular domain; Mouse; Adipocyte; C1q and collagen domain-containing protein; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipose most abunda; Adiponectin; 30 kDa adipocyte complement related protein; ACRP 30; Adipocyte C1q and collagen domain containing protein; Adipocyte complement related 30 kDa protein; Adipocyte complement related protein of 30 kDa; Adipose most abundant gene transcript 1; APM 1; GBP 28; Gelatin binding protein

other names :

adiponectin; Adiponectin; adiponectin; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; gelatin-binding protein 28; adiponectin, C1Q and collagen domain containing; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipose most abundant gene transcript 1 protein; apM-1; Gelatin-binding protein

other gene names :

ADIPOQ; ADIPOQ; ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1; ACDC; ACRP30; APM1; GBP28; ACRP30; apM-1

uniprot entry name :

ADIPO_HUMAN

clonality :

Monoclonal

isotype :

IgG1, k

clone :

1G12

host :

Mouse

reactivity :

Human, Mouse

sequence length :

244

purity :

By protein-G affinity chromatography

form :

Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.

concentration :

1mg/ml

storage stability :

Can be stored at 4 degree C. For long term storage, aliquot and store at -20 degree C. Avoid repeated freezing and thawing cycles.

tested application :

ELISA (EIA), Western Blot (WB) (Recombinant protein,Cell lysate)

app notes :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:250 ~ 1,000. Recommended starting dilution is 1:500. Please note that this antibody (1G12) has the specificity against globular domain of adiponectin.

other info1 :

Antigen Species: Human. Clone: Anti-human adiponectin mAb, clone 1G12, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Acrp30 protein. Immunogen: Recombinant human adiponectin (15-244aa) purified from E Coli

products categories :

Hormones & Cytokines

products description :

Human Adiponectin, also referred to as AdipoQ, Acrp30, apm-1 or GBP28, is a secreted protein expressed exclusively in differentiated adipocyte(adipokine). Adiponectin contains a modular structure comprising an N-terminal collagenous domain followed by a C-terminal globular domain(gAcrp30). Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Plasma levels of adiponectin are reduced in obese humans, and decreased levels are associated with insulin resistance and hyperinsulinemia.

products references :

Maeda k. et al., (1996) Biochem Biophys Res Commun. 221:286-9. Berg AH. et al., (2001) Nat Med; 7:947-53 Berg AH. et al., (2002) Trends Endocrinol Metab. 13: 84-89. Yamauchi T. et al., (2002) Nat Med. 8:1288-95

ncbi gi num :

4757760

ncbi acc num :

NP_004788

ncbi gb acc num :

NM_004797.3

ncbi mol weight :

26,414 Da

ncbi pathways :

AMPK Signaling Pathway 198868!!AMPK Signaling Pathway 989139!!AMPK Signaling Pathway 992181!!Adipocytokine Signaling Pathway 83093!!Adipocytokine Signaling Pathway 505!!Adipogenesis Pathway 198832!!Developmental Biology Pathway 477129!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862188!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862314!!PPAR Signaling Pathway 83042

ncbi summary :

This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormonal processes. Mutations in this gene are associated with adiponectin deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010]

size :

0.05 ml

price :

240 USD

more info or order :

MyBioSource product webpage