product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Thyroid Peroxidase (TPO)
catalog :
MBS197032
quantity :
0.1 mg
price :
1170 USD
more info or order :
product information
catalog number :
MBS197032
products type :
Recombinant Protein
products full name :
Recombinant Human Thyroid Peroxidase (TPO)
products short name :
Recombinant Human Thyroid Peroxidase (TPO)
host :
Insect Cell
specificity :
Recombinant Human Thyroid Peroxidase (TPO)
purity :
Greater than 95% as determined by SDS-PAGE. Identity confirmed by MALDI mass spectrometry.
form :
Lyophilized from 20mM Tris-HCl, pH 8.0, 250mM NaCl, 0.1mM KI, 5% D-mannitol. Reconstitute with sterile deionized H2O.
storage stability :
Store at 20 degree C in lyophilized form. After reconstitution, store at -70 degree C. Avoid repeated freezing and thawing.
products description :
Thyroid peroxidase (TPO) is an integral apical membrane glycoprotein of thyroid follicular cells and plays a key role in thyroid hormone biosynthesis. It is a homodimer comprised of two identical subunits of approx. 100kDa. TPO is one of the main autoantigenic targets in autoimmune thyroid disease of humans. Anti-TPO autoantibodies are present in 90% of cases of Hashimoto's thyroiditis and 75% of cases of Graves' disease. Recombinant human TPO produced in insect cells corresponds to aa 19-846 (calculated molecular weight approx. 92kDa) of the soluble extracellular domain of human TPO. It does not contain any tags. It is purified by specific monoclonal antibody-based affinityand ion exchange chromato-graphic methods. In SDS-PAGE, two bands in the region of 100-110kDa are observed due to differential glycosyl- ation of the protein. Immunoreactivity of rhuTPO is confirmed by ELISA with patient serum samples containing anti-TPO autoantibodies.
size :
0.1 mg
price :
1170 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!