product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Leptin
catalog :
MBS197016
quantity :
0.2 mg
price :
195 USD
more info or order :
citations: 1
Reference
Al Khalaf H, Amir M, Al Mohanna F, Tulbah A, Al Sayed A, Aboussekhra A. Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity. Mol Cell Biol. 2017;37: pubmed publisher
product information
catalog number :
MBS197016
products type :
Recombinant Protein
products full name :
Recombinant Human Leptin
products short name :
Leptin (Anti-Obesity Protein) (rHuLeptin)
products name syn :
Recombinant Human Leptin (Anti-Obesity Protein) (rHuLeptin)
other names :
leptin; leptin; obesity homolog; leptin
other gene names :
lep; ob; xlep
host :
E Coli
specificity :
Recombinant Human Leptin (Anti-Obesity Protein) (rHuLeptin)
purity :
Greater than 95% by RP-HPLC, anion-exchange chromatography; reducing and non-reducing SDS-PAGE, silver stain. Purification: Chromatographic
form :
Sterile filtered, lyophilized.
storage stability :
Lyophilized product is stable at room temperature, but should be stored desiccated at -20 degree C. Upon reconstitution, store at 4 degree C. Avoid repeated freeze-thaw cycles.
other info1 :
Dimers/Aggregates: <1% by SDSPAGE. Biological Activity: Fully biologically active compared to reference standards. ED50 determined by the leptin dependent stimulation of human OB-R transfected murine BaF3 cells is 0.5-1.6 ng/ml.
other info2 :
Endotoxin Level: <0.1 ng/ug. Protein Content: Determined spectrophotometrically at 280nm (extinction coefficient 0.878) and by RPHPLC analysis against a calibrated standard. Solubility: Soluble in water and most aqueous buffers above and below the isoelectric point. Dialyzed against 45mM sodium bicarbonate prior to lyophilization. Stabilizer: None. Preservatives: None
products categories :
Recombinant Proteins
products description :
Recombinant Human Leptin produced in E. coli is a single, non-glycosylated, polypeptide chain containing 147 amino acids with a molecular mass of 16,240 daltons. This product has full biological activity.
ncbi gi num :
148233267
ncbi acc num :
NP_001089183.1
ncbi gb acc num :
NM_001095714.1
ncbi pathways :
Adipocytokine Signaling Pathway (119298); Adipocytokine Signaling Pathway (505); Cytokine-cytokine Receptor Interaction Pathway (119282); Cytokine-cytokine Receptor Interaction Pathway (460); Jak-STAT Signaling Pathway (84661); Jak-STAT Signaling Pathway (488); Neuroactive Ligand-receptor Interaction Pathway (119283); Neuroactive Ligand-receptor Interaction Pathway (462)
size1 :
0.2 mg
price1 :
195 USD
size2 :
1 mg
price2 :
280
size3 :
5 mg
price3 :
615
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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