catalog number :
MBS197011
products type :
Recombinant Protein
products full name :
Recombinant Human Insulin-Like Growth Factor I(rHuIGF-1)
products short name :
Insulin-Like Growth Factor I (rHuIGF-I)
products name syn :
Recombinant Human Insulin-Like Growth Factor I (rHuIGF-I)
other names :
insulin-like growth factor I; Insulin-like growth factor 1 (Somatomedin C); insulin-like growth factor 1; MGF; IGF-IA; IGF-IB; somatomedin-C; OTTHUMP00000195080; OTTHUMP00000195081; OTTHUMP00000195082; OTTHUMP00000195083; OTTHUMP00000195084; mechano growth factor; insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; insulin-like growth factor 1 (somatomedin C); Somatomedin-C; Mechano growth factor; MGF
other gene names :
IGF1; IGF1; IGFI; IGF-I; IGF1A; IBP1
uniprot entry name :
Q5U743_HUMAN
specificity :
Recombinant Human Insulin-Like Growth Factor I (rHuIGF-I)
purity :
Greater than 98% by RP-HPLC, anion-exchange chromatography; reducing and non-reducing SDS-PAGE, silver stain. Purification: Chromatographic
form :
Sterile filtered, lyophilized.
storage stability :
Lyophilized product is stable at room temperature for 3 weeks. Store lyophilized product desiccated at -20 degree C. Upon reconstitution, store at 4 degree C for 2-7 days or aliquot and store at -20 degree C. For long-term storage add either HSA or BSA to 0.1%. Avoid repeated freeze-thaw cycles.
other info1 :
Dimers/Aggregates: <1% by SDSPAGE. Biological Activity: Fully biologically active compared to reference standards. Specific activity is 1 x 10^6 IU/mg. Biological activity at 0.2-20 ng/ml.
other info2 :
Endotoxin Level: <0.1 ng/ug. Protein Content: Determined spectrophotometrically at 280nm (0.502 ext. coeff), and by RP-HPLC analysis against a calibrated standard. Solubility: Reconstitute the lyophilized product in sterile water not less than 100 ug/ml. Product was dialyzed against 50mM acetate prior to lyophilization. Stabilizer: None. Preservatives: None
products categories :
Recombinant Proteins
products description :
Recombinant Human IGF-1 produced in E. coli is a single, non-glycosylated polypeptide chain containing 70 amino acids with a molecular mass of 7,655 daltons. This product has full biological activity.
ncbi acc num :
AAA52789.1
ncbi mol weight :
17,026 Da
ncbi pathways :
Adipogenesis Pathway 198832!!Aldosterone-regulated Sodium Reabsorption Pathway 130626!!Aldosterone-regulated Sodium Reabsorption Pathway 130590!!Androgen Receptor Signaling Pathway 198806!!Apoptosis Pathway 198797!!Diabetes Pathways 105902!!Dilated Cardiomyopathy Pathway 121494!!Dilated Cardiomyopathy Pathway 121285!!Endochondral Ossification Pathway 198812!!Focal Adhesion Pathway 198795
ncbi summary :
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.
uniprot summary :
Subcellular location: Secreted. By similarity RuleBase RU000406. Sequence similarities: Belongs to the insulin family. RuleBase RU000406