catalog number :
MBS197003
products type :
Recombinant Protein
products full name :
Recombinant Human Acidic FGF1
products short name :
acidic FGF (FGF-1)
products name syn :
Recombinant human acidic FGF (FGF-1); Human Fibroblast Growth Factor 1
other names :
fibroblast growth factor 1 (acidic); fibroblast growth factor 1 (acidic); fibroblast growth factor 1 (acidic); acidic fgf; fibroblast growth factor 1 (acidic)
other gene names :
fgf1; aFGF; ecgf; fgfa; ecgfa; ecgfb; fgf-1; hbgf1; HBGF-1; glio703; ecgf-beta; fgf-alpha
host :
Genetically engineered E Coli
specificity :
Recombinant human acidic FGF (FGF-1). In the presence of heparin, 45101 binds to most cells that express FGF receptor; binds to all known isoforms of FGF receptor.
purity :
>90%. Purification: Purified by heparin affinity chromatography and HPLC; single band at 1 ug on silver-stained SDS-PAGE.
storage stability :
This product is stable for at least one (1) year at -20 degree C to -70 degree C. Keep frozen until use. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
other info1 :
Biological Activity: The activity of acidic FGF at 1-10 ng/ml is determined by a cellular proliferation assay using mouse fibroblasts. The optimal concentration of this product for use with other cell types must be determined by the end user.
other info2 :
Diluent: 0.1% trifluoroacetic acid + 40% acetonitrile. Preservatives: None. Dilutions Instructions: Dilute with either 0.1% TFA/40% acetonitrile or PBS/0.1% CHAPS for best stability and to prevent absorption of product on walls of vessels.
products categories :
Recombinant Growth Factors
products references :
Burgess, WH and Maciag, T (1989) Annual Rev Boichem 58: 575.
ncbi acc num :
NP_001136293.1
ncbi gb acc num :
NM_001142821.1
ncbi mol weight :
15,000 daltons
ncbi pathways :
Downstream Signaling Of Activated FGFR Pathway (371714); FGFR Ligand Binding And Activation Pathway (371703); FGFR1 Ligand Binding And Activation Pathway (371704); FGFR1b Ligand Binding And Activation Pathway (371705); FGFR1c Ligand Binding And Activation Pathway (371706); FGFR2 Ligand Binding And Activation Pathway (371707); FGFR2b Ligand Binding And Activation Pathway (371708); FGFR2c Ligand Binding And Activation Pathway (371709); FGFR3 Ligand Binding And Activation Pathway (371710); FGFR3b Ligand Binding And Activation Pathway (371711)