catalog number :
MBS194495
products full name :
Calcineurin A Polyclonal Antibody
products short name :
Calcineurin A (Catalytic)
other names :
calcineurin A; calcineurin A
reactivity :
Human, mouse, rat, rabbit, canine, bovine, porcine, chicken, monkey, hamster, drosophila
sequence positions :
264-283
specificity :
Calcineurin A (Catalytic) Antibody. This antibody recognizes human, mouse, rat, rabbit, canine, bovine, porcine, chicken, monkey, hamster, and Drosophila Calcineurin A.
form :
200ug Supplied as Protein A-purified antibody in PBS, 0.09% sodium azide, 50% glycerol.
storage stability :
Store at or below -20 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Immunoprecipitation; Western Blot
app notes :
Western blot: Use at 2 ug/ml. Immunoprecipitation: Use at 10 ug/ml. Positive controls: HeLa cell lysate, rat brain tissue extract, mouse brain tissue extract.
other info1 :
Antigen: Peptide corresponding to aa 264-283 of human Calcineurin A conjugated to KLH. This sequence is identical in rat and mouse calcineurin A.
other info2 :
Dilution Instructions: Dilute in PBS or medium that is identical to that used in the assay system.
products description :
Calcineurin is a Ca+2/calmodulindependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit (61kDa) and a myristylated regulatory B subunit (19kDa) that binds calcium. It controls the translocation of nuclear factors from the cytosol into the nucleus of activated T cells. Calcineurin is a target of immunosuppressive drugs such as cyclosporin A and FK506.
ncbi acc num :
NP_001037025.1
ncbi gb acc num :
NM_001043560.1