catalog number :
MBS194368
products full name :
Tet Repressor Polyclonal Antibody
products short name :
Tet Repressor
products name syn :
Tet Repressor
other names :
Tet repressor; Tetracycline repressor protein class E
uniprot entry name :
TETR5_ECOLX
specificity :
Tet Repressor [This affinity purified rabbit polyclonal antibody detects Tet Repressor protein. Useful in Western Blot]. This antibody detects Tet repressor protein. The Tet repressor protein regulates transcription of a family of tetracycline resistance determinants in Gram-negative bacteria. The Tet system is the most widely used regulatory system for conditional gene expression in eukaryotic cells. TetR can be used for that purpose in some organisms without further modifications. In mammals and in a large variety of other organisms, however, eukaryotic transcriptional activator or repressor domains are fused to TetR to turn it into an efficient regulator.
purity :
Affinity Purified
storage stability :
Store at 2-8 degree C for up to 3 months or below -20 degree C for longer storage. Avoid repeated freeze-thaw cycles.
tested application :
Western Blot
app notes :
Western Blot 1 ug/ml
other info1 :
Antigen: Tet Repressor Protein
other info2 :
Buffer: Phosphate buffered saline containing 1 mg/ml BSA and 0.02% sodium azide
products categories :
DNA / RNA Antibodies
ncbi acc num :
CAA32196.1
ncbi mol weight :
23,585 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
uniprot summary :
Function: TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to tetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. Sequence similarities: Contains 1 HTH tetR-type DNA-binding domain.