product summary
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company name :
MyBioSource
product type :
antibody
product name :
MAP-1 Polyclonal Antibody
catalog :
MBS194297
quantity :
0.1 mg
price :
345 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
product information
catalog number :
MBS194297
products type :
Antibody
products full name :
MAP-1 Polyclonal Antibody
products short name :
MAP-1
products name syn :
MAP-1
other names :
MAP-1; Modulator of apoptosis 1; modulator of apoptosis 1; paraneoplastic antigen like 4; modulator of apoptosis 1; Paraneoplastic antigen Ma4
other gene names :
MOAP1; MOAP1; MAP-1; PNMA4; MOAP1; PNMA4
uniprot entry name :
MOAP1_HUMAN
clonality :
Polyclonal
host :
Rabbit
sequence length :
351
specificity :
MAP-1 [This rabbit antibody recognizes aa 2-16 of human MAP-1 (Modulator of Apoptosis Protein), a novel Bax-associating protein.]. This antibody recognizes human MAP-1 (Modulator of Apoptosis Protein), a novel Bax-associating protein. MAP-1 mediates caspase-dependent apoptosis in mammalian cells when overexpressed. MAP-1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-xL of the Bcl-2 family.
form :
100 ug IgG in 100 ul PBS, pH7.4, purified by immunoaffinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting: use at 1:500-1:1,000 dilution. A band of approx. 39 kD is detected.
other info1 :
Antigen: Peptide corresponding to aa 337-351 of human MAP-1.
other info2 :
Stabilizer: None. Preservatives: 0.02% sodium azide. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Apoptosis Antibodies
ncbi gi num :
11139669
ncbi acc num :
AAG31786.1
uniprot acc num :
Q96BY2
ncbi mol weight :
39,513 Da
ncbi summary :
The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis. [provided by RefSeq]
uniprot summary :
MOAP1: Required for death receptor-dependent apoptosis. When associated with RASSF1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Belongs to the PNMA family. Chromosomal Location of Human Ortholog: 14q32. Cellular Component: mitochondrial outer membrane; mitochondrion; cytoplasm; cytosol. Molecular Function: protein binding; ubiquitin protein ligase binding. Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; induction of apoptosis via death domain receptors; protein insertion into mitochondrial membrane during induction of apoptosis; positive regulation of apoptosis
size1 :
0.1 mg
price1 :
345 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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