catalog number :
MBS194207
products full name :
c-myc Affinity Purified Antibody, HRP Conjugated
products short name :
c-myc HRP
products name syn :
c-myc HRP
other names :
c-myc; C-myc protein; myc proto-oncogene protein; OTTHUMP00000158589; OTTHUMP00000227763; proto-oncogene c-Myc; transcription factor p64; class E basic helix-loop-helix protein 39; avian myelocytomatosis viral oncogene homolog; v-myc avian myelocytomatosis viral oncogene homolog; myc-related translation/localization regulatory factor; v-myc myelocytomatosis viral oncogene homolog (avian)
other gene names :
MYC; c-myc; MRTL; c-Myc; bHLHe39
uniprot entry name :
Q6LBK7_HUMAN
specificity :
c-myc HRP [Goat polyclonal antibody to c-myc HRP Conjugate]
storage stability :
Store at 4 degree C; stable for one year
tested application :
ELISA, Western Blot, Immunohistochemistry, Immunocytochemistry
app notes :
ELISA: 0.01 - 0.1 ug/ml. Western Blot: Colorimetric: 0.1-1 ug/ml, Chemiluminescent: 0.03-1 ug/ml. Immunohistochemistry/Immunocytochemistry: 0.5-2 ug/ml
other info1 :
Antigen: c-myc (EQKLISEEDL) coupled to KLH.
other info2 :
Buffer: 50mM HEPES, pH 7.1, 0.1M NaCl. Stabilizer: 0.2% BSA. Preservatives: 0.01% thimerosal
products categories :
Epitope Tag Antibodies
ncbi mol weight :
7,012 Da
ncbi pathways :
Acute Myeloid Leukemia Pathway 83117!!Acute Myeloid Leukemia Pathway 529!!Apoptosis Pathway 198797!!Bladder Cancer Pathway 83115!!Bladder Cancer Pathway 527!!C-MYB Transcription Factor Network Pathway 138073!!C-MYC Pathway 169344!!CD40/CD40L Signaling Pathway 138061!!Cell Cycle, Mitotic Pathway 105765!!Cell Cycle Pathway 83054
ncbi summary :
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]