This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
c-Jun Polyclonal Antibody
catalog :
MBS194196
quantity :
0.1 mg
price :
405 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
pig
application :
western blot
product information
catalog number :
MBS194196
products type :
Antibody
products full name :
c-Jun Polyclonal Antibody
products short name :
c-Jun
products name syn :
c-Jun Antibody; c-Jun
other names :
c-Jun; Transcription factor AP-1; transcription factor AP-1; AP1; activator protein 1; proto-oncogene c-jun; V-jun avian sarcoma virus 17 oncogene homolog; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog
other gene names :
C-JUN; JUN; Jun
uniprot entry name :
JUN_PIG
clonality :
Polyclonal
host :
Rabbit
specificity :
c-Jun Antibody [Rabbit polyclonal antibody to c-Jun]. This antibody recognizes human, monkey, rat, mouse, hamster, rabbit, ovine, porcine, bovine, canine, chicken, guinea pig, Xenopus, and Drosophila c- Jun.
form :
25 ug, Supplied as affinity purified antibody at 1 mg/ml in borate buffered saline, pH 8.4.
storage stability :
Store frozen product at or below -20 degree C. Thawed product may be stored for 2-4 weeks at 4 degree C. For optimal storage, aliquot to smaller portions and store at -20 degree C to -70 degree C. Avoid repeated freeze/thaw cycles.
tested application :
Western Blot, Immunoblot
app notes :
Western Blot: Use at 1 ug/ml. A band of approximately 46 kD is detected on immunoblots and corresponds to the molecular weight of c-Jun.
other info1 :
Antigen: Peptide corresponding to aa 266-285 of human c-Jun.
other info2 :
Stabilizer: None. Preservatives: 0.02% Sodium Azide. Dilutions Instructions: Dilute in PBS or medium that is identical to that used in the assay system.
products categories :
Neuroscience and Signal Transduction Antibodies
ncbi gi num :
1911701
uniprot acc num :
P56432
ncbi mol weight :
35,629 Da
ncbi pathways :
Activated TLR4 Signalling Pathway 370198!!Activation Of The AP-1 Family Of Transcription Factors Pathway 370187!!B Cell Receptor Signaling Pathway 84493!!B Cell Receptor Signaling Pathway 492!!Chagas Disease (American Trypanosomiasis) Pathway 147807!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Colorectal Cancer Pathway 84513!!Colorectal Cancer Pathway 518!!ErbB Signaling Pathway 84461!!ErbB Signaling Pathway 458
uniprot summary :
Function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Subunit structure: Heterodimer with either FOS or BATF3 or ATF7. By similarity. The ATF7/JUN heterodimer is essential for ATF7 transactivation activity. Interacts with MYBBP1A, SP1, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA. Interacts with HIVEP3. Component of the SMAD3/SMAD4/JUN/FOS/complex which forms at the AP1 promoter site. The SMAD3/SMAD4 heterodimer acts syngernistically with the JUN/FOS heterodimer to activate transcription in response to TGF-beta. Interacts (via its basic DNA binding and leucine zipper domains) with SMAD3 (via an N-terminal domain); the interaction is required for TGF-beta-mediated transactivation of the SMAD3/SMAD4/JUN/FOS/complex. By similarity. Interacts with RNF187. Subcellular location: Nucleus. Post-translational modification: Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC. Sequence similarities: Belongs to the bZIP family. Jun subfamily.Contains 1 bZIP domain.
size :
0.1 mg
price :
405 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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