catalog number :
MBS194181
products full name :
Bmf (NT) Polyclonal Antibody
products short name :
Bmf (NT)
products name syn :
Bmf (NT)
specificity :
Bmf (NT) [This rabbit antibody recognizes an epitope of aa 2-14 at the N-terminus of human Bmf (Bcl-2-Modifying Factor), a novel BH3-only protein.]. This antibody recognizes an epitope at the N-terminus of human Bmf (Bcl-2- Modifying Factor), a novel BH3-only protein. In healthy cells, Bmf associates with the dynein light chain 2 component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiaing the downstream apoptotic program. Bmf is constitutively expressed in many tissues.
form :
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting: use at 2 ug/ml. In immunoblots, a band of 25 kD is detected. Positive control: HepG2 or 293 cell lysates.
other info1 :
Antigen: Peptide corresponding to aa 2-14 of human Bmf.
other info2 :
Stabilizer: None. Preservatives: 0.02% sodium azide. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Apoptosis Antibodies