catalog number :
MBS194144
products full name :
Anti-Survivin (mouse CT) Antibody
products short name :
mSurvivin (CT)
products name syn :
Anti-mSurvivin (CT); Survivin (mouse CT)
specificity :
Anti-mSurvivin (CT) [Rabbit antibody to peptide corresponding to aa 128-140 of mouse survivin.]. This antibody recognizes mouse survivin (17 kD).
form :
100 ug IgG in 200 ul PBS, pH 7.4, purified by immunoaffinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting: use at 1:500-1:1,000 dilution. Positive control: Mouse spleen cell lysate.
other info1 :
Antigen: Peptide corresponding to aa 128- 140 of mouse survivin.
other info2 :
Stabilizer: None. Preservatives: 0.02% sodium azide. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Apoptosis Antibodies
products description :
Apoptosis is related to many diseases and is triggered by a variety of stimuli including members of the TNF family. Apoptosis can be prevented by the inhibitor of apoptosis proteins (IAPs). IAPs constitute a conserved gene family that binds to and inhibits cell death proteases. A novel IAP has been identified and designated survivin. Survivin interacts with the processed form of caspase-3 and inhibits its proteolytic activity. Survivin is expressed predominantly in tissues of embryos, transformed cell lines, and many human cancers.