product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Ku80 Antibody
catalog :
MBS194113
quantity :
0.1 mg
price :
320 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
fruit fly
application :
western blot
more info or order :
product information
catalog number :
MBS194113
products type :
Antibody
products full name :
Anti-Ku80 Antibody
products short name :
Ku80
products name syn :
Ku80
other names :
Ku80; CG18801 gene product from transcript CG18801-RA; Ku80; CG18801-PA; Ku80-PA
other gene names :
Ku80; BG:DS09217.6; CG18801; DmelCG18801; DmKu80; Ku; ku80; KU80
host :
Rabbit
specificity :
Ku80 [Human, mouse, rat, and hamster Ku80]. This antibody recognizes human, mouse, rat, and hamster Ku80.
form :
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting: use at 1:500 dilution. A band of approximately 80 kDa is detected. Positive control: A431 and AR42J whole cell lysates.
other info1 :
Immunogen: Synthetic peptide corresponding to amino acids 323-338 (FSKVDEEQMKYKSEGK) of Ku80 conjugated to KLH at the C-terminus.
other info2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
DNA / RNA Antibodies
products description :
Telomere length maintenance, essential to chromosome stability and genome integrity, is regulated by telomerase and telomere-associated factors. The Ku proteins are eukaryotic nuclear proteins involved in DNA repair and telomere maintenance. They exist as a heterodimer of 70 and 80 kDa subunits (Ku 70 and Ku 80). Ku heterodimers bind to DNA ends at telomeres and at double-strand breaks where they interact with DNA-dependent protein kinase (DNA PK) and participate in targeting of DNA PK to DNA. The Ku proteins may participate in DNA repair and replication, cell signaling, proliferation, transcriptional activation, and apoptosis.
products references :
Park SJ et al. (2004) J Biol Chem 279:6046-55.
ncbi gi num :
24584494
ncbi acc num :
NP_609767.2
ncbi gb acc num :
NM_135923.2
ncbi pathways :
DNA Repair Pathway (365717); Double-Strand Break Repair Pathway (365738); Non-homologous End-joining Pathway (3082); Nonhomologous End-joining (NHEJ) Pathway (365751)
size1 :
0.1 mg
price1 :
320 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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