catalog number :
MBS194097
products full name :
Anti-Hippostatin/KLK11 Antibody
products short name :
Hippostatin/KLK11
products name syn :
Anti-Hippostatin/KLK11; KLK11
specificity :
Anti-Hippostatin/KLK11 [This antibody recognizes human hippostatin/KLK11 (35 kDa) which has 86% sequence homology with mouse and rat.]
form :
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting : use at 1:500 dilution. Positive control: LNCaP cell lysate
other info1 :
Immunogen: Synthetic peptide corresponding to aa residues 68-82 (YIVHLGQHNLQKEEG) of human Hippostatin conjugated to KLH at the C-terminus.
other info2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Cancer Research Products
products description :
Hippostatin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostatin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
products references :
Diamandis,E.P. et al. (2002) Cancer Res. 62: 295-300. Nakamura,T et al. (2003) Prostate 54: 299-305.