catalog number :
MBS194068
products full name :
Anti-Dnase II (CT) Antibody
products short name :
Dnase II (CT)
products name syn :
Anti-Dnase II (CT); DNase II (CT)
other names :
DNase II; ORF FPV032 DNase II; DNase II
other gene names :
FPV032; FPV032
uniprot entry name :
Q9J5H0_FOWPN
specificity :
Anti-Dnase II (CT) [Rabbit antibody to peptide corresponding to aa 347-360 of human DNase II.]. This antibody recognizes human Dnase II alpha chain (32 kD). It does not react with the 12 kD beta chain.
form :
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting: use at 1:500-1:1,000 dilution. Positive control: Tissue lysate of human spleen
other info1 :
Antigen: Peptide corresponding to aa 347-360 of human DNase II.
other info2 :
Stabilizer: None. Preservatives: 0.02% sodium azide. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Apoptosis Antibodies
products description :
Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of the caspase family, caspase-activated DNase, and several novel proteins including AIF and Acinus. DNase II causes both chromatin condensation and DNA fragmentation. The genes encoding human, porcine, and murine DNase II have been cloned. The DNase II gene encodes a 40 kD proenzyme. The mature enzyme consists of two non-identical subunits, the 32 kD ( alpha ) and 12 kD ( beta ) chains, generated by proteolytic processing. Overexpression of DNase II induces chromatin condensation. DNase II is ubiquitously expressed in human tissues.
ncbi acc num :
NP_038995.1
ncbi gb acc num :
NC_002188.1
ncbi mol weight :
26,772 Da