catalog number :
MBS194039
products full name :
Anti-Bonzo (NT2) Antibody
products short name :
Bonzo (NT2)
products name syn :
Anti-Bonzo (NT2); HIV Co-Receptor Bonzo (NT)
specificity :
Anti-Bonzo (NT2) [Rabbit antibody to peptide corresponding to aa 11-25 at N-terminus of human Bonzo. The sequence of this peptide differs from those of African green monkey and macaque by one or two amino acids, respectively.]. This antibody recognizes human Bonzo (40 kD).
form :
100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting: use at 1:500 dilution. Positive control: Tissue lysate of human spleen.
other info1 :
Antigen: Peptide corresponding to aa 11-25 at the N-terminus of human Bonzo. The sequence of this peptide differs from those of African green monkey and macaque by one or two amino acids, respectively.
other info2 :
Stabilizer: None. Preservatives: 0.02% sodium azide. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Infectious Disease Antibodies
products description :
Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors in addition to CD4 to infect target cells. Some G protein-coupled receptors in the chemokine receptor family, including CCR5, CXCR4, CCR3, and CCR2b, have previously been identified as HIV coreceptors. An orphan G proteincoupled receptor designated Bonzo was recently cloned and identified as a HIV- 1 and -2 and SIV coreceptor (also called STRL33 and TYMSTR). The messenger RNA for Bonzo is expressed in lymphoid tissues and activated peripheral blood lymphocytes
ncbi pathways :
Focal Adhesion Pathway 83067!!Focal Adhesion Pathway 478!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Salmonella Infection Pathway 375172!!Salmonella Infection Pathway 375149