catalog number :
MBS194020
products full name :
Anti-AIF (IN) Antibody
products short name :
AIF (IN)
products name syn :
Anti-AIF (IN); AIF (IN)
specificity :
Anti-AIF (IN) [Rabbit antibody to peptide corresponding to aa 517-531 of human AIF. Recognizes human, mouse, and rat AIF.]. This antibody recognizes human, mouse, and rat AIF (67 kD).
form :
100 ug IgG in 200 ul PBS, pH 7.4, purified by immunoaffinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting: use at 1:500-1:2,000 dilution. Positive control: Whole cell lysate from K562 cells.
other info1 :
Antigen: Peptide corresponding to aa 517-531 of human AIF. This sequence is identical to those of mouse and rat AIF.
other info2 :
Stabilizer: None. Preservatives: 0.02% sodium azide. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Apoptosis Antibodies
products description :
Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of caspases, caspase-activated DNase, and several other proteins. A novel protein that causes chromatin condensation and DNA fragmentation has been designated Apoptosis Inducing Factor (AIF). AIF localizes in mitochondria and translocates to the nucleus when apoptosis is induced. This event is followed by the release of chytochrome c and caspase-9 from mitochondria. AIF is highly conserved between human and mouse and widely expressed in different cell types and tissues.