product summary
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company name :
MyBioSource
product type :
antibody
product name :
Anti-Hsp70 Monoclonal Antibody
catalog :
MBS190533
quantity :
0.1 mg
price :
380 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3A3
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
product information
catalog number :
MBS190533
products type :
Antibody
products full name :
Anti-Hsp70 Monoclonal Antibody
products short name :
Hsp70 clone 3A3
other names :
HSP70
products gene name :
Hsp70
clonality :
Monoclonal
isotype :
IgG1
clone :
3A3
host :
Mouse
reactivity :
Human, mouse, fish, rat, avian, amphibian, drosophila, yeast
specificity :
Hsp70 clone 3A3. This antibody recognizes human, mouse, fish, rat, avian, amphibian, Drosophila, and yeast Hsp70, Hsc70, p75, and, following heat shock, Hsp72.
form :
100ug Protein G-purified antibody in PBS, pH 7.4 and 50% glycerol.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C.
tested application :
Immunoblot; Immunohistochemistry; Immunoprecipitation; Immunoprecipitation; Immunocytochemistry
app notes :
Immunoblotting: use at 0.2ug/ml (ECL). A band of ~70 kDa is detected. Immunoprecipitation: use at 1-2ug/ml. Immunohistochemistry/Immunocytochemistry:use at 2 ug/ml. User should determine optimal concentrations for their applications. Positive control: Heat-shocked HeLa cell lysate.
other info1 :
Antigen: Recombinant human Hsp70 expressed in E. coli. Preservative: 0.09% sodium azide
other info2 :
Dilution Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products description :
Hsp70 binds ATP with high affinity and possesses a weak ATPase activity which can be stimulated by binding to unfolded proteins and synthetic peptides. Hsp70 recognizes and binds to nascent polypeptide chains as well as partially folded intermediates of proteins preventing their aggregation and misfolding. The binding of ATP triggers a critical conformational change leading to the release of the bound protein. The ability of Hsp70 to undergo cycles of binding and release from hydrophobic stretches of partially unfolded proteins is the basis for their role in a variety of intracellular functions such as protein synthesis, protein folding and oligomerization and protein transport.
ncbi gi num :
476003
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
size1 :
0.1 mg
price1 :
380 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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