catalog number :
MBS190495
products full name :
Yersinia pestis V Antigen Monoclonal Antibody
products short name :
Yersinia pestis V antigen
products name syn :
Yersinia pestis V antigen
specificity :
Yersinia pestis V antigen [These antibodies specifically recognize Y.pestis V antigen. They do not cross react with Y.pestis capsular F1 antigen.]. These antibodies specifically recognize Y. pestis V antigen. They do not cross-react with Y. pestis capsular F1 antigen.
purity :
Purified by Protein G affinity chromatography and are supplied in PBS, pH 7.4, containing 0.1% sodium azide as preservative.
storage stability :
This antibody is stable for at least one (1) year at 4 degree C or -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
ELISA, Immunoblot
app notes :
Immunoblotting: End-user should determine optimal concentration. We recommend testing a concentration range of 1-10ug/ml. A band of 37 kDa is detected. ELISA: End-user should determine optimal concentration for their sample. Sandwich ELISA: use 18772 as coating antibody and 18773 as detect antibody.
other info1 :
Antigen: Recombinant full-length Y. pestis V antigen.
other info2 :
Preservatives: 0.1% NaN3. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
BioWarfare Antibodies
products description :
Y. pestis, the causative agent of plague, has low-Ca^+2 response (LCR) virulence plasmids that encode a set of secreted virulence proteins including Yersinia outer proteins (YOPS) and the V antigen, LcrV. Some of the YOPS play a role in adherence to eukaryotic cells while others are targeted into a eukaryotic cell at the site of adherence. The YOPS derange cellular signaling and cytoskeletal functions necessary for host defenses such as phagocytosis. LcrV is a secreted anti-host component with direct immunomodulatory effects. LcrV expression is involved in targeting of YOPS to host cells and is required for cytotoxicity.