product summary
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company name :
MyBioSource
product type :
antibody
product name :
FKBP52 Monoclonal Antibody
catalog :
MBS190476
quantity :
0.1 mg
price :
415 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunoprecipitation
more info or order :
product information
catalog number :
MBS190476
products type :
Antibody
products full name :
FKBP52 Monoclonal Antibody
products short name :
FKBP52
products name syn :
FKBP52 Monoclonal Antibody; FKBP52
clonality :
Monoclonal
isotype :
IgG1
host :
Mouse
specificity :
FKBP52 Monoclonal Antibody [Mouse monoclonal antibody recognizes FKBP52 of multiple species.]. This antibody recognizes human, mouse, rat, dog, and hamster FKBP52.
form :
100ug in PBS, pH 7.4, purified by Protein G affinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
tested application :
Immunoblot, Immunohistochemistry, Immunoprecipitation
app notes :
Immunoblotting: use at 0.5-1ug/ml. A band of ~52 kDa is detected. Immunohistochemistry: use at 4-5ug/ml. Immunoprecipitation: 5ug on 10-20ul Protein A-Sepharose + 100ul sample. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: HeLa cell lysate, rat kidney and rat/mouse testes tissue extracts.
other info1 :
Antigen: Recombinant full-length FKBP52 with an N-terminal polyhistidine tag.
other info2 :
Preservatives: 0.09% sodium azide. Other Additives: 50% glycerol. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Heat Shock and Stress Proteins
products description :
FK506-binding proteins, FKBP51 and FKBP52, are high molecular weight immunophilins that are part of the mature glucocorticoid receptor heterocomplex. The N-terminal domains of these proteins bind FK506 and have peptidyl-prolyl isomerase activity that converts prolyl peptide bonds within target proteins from cis- to trans- proline. The C-terminal domains contain the tetratricopeptide repeats that are involved in protein-protein interactions with Hsp90. Although FKBP52 and FKBP51 share ~75% sequence similarity, they affect hormone binding by glucocorticoid receptors differently and have different Hsp90-binding characteristics. In addition, FKBP51 is linked to the progesterone receptor while FKBP52 is linked to progesterone, androgen, and glucocorticoid receptors.
products references :
Nair, SC et al. 1997 Mol Cell Biol 17: 594- 603
size1 :
0.1 mg
price1 :
415 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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