antibody

TATA-Binding Protein Monoclonal Antibody

MBS190431

0.2 mg

340 USD

monoclonal

mouse

nonconjugated

western blot, immunoprecipitation

Antibody

TATA-Binding Protein Monoclonal Antibody

TATA - Binding Protein

Anti-TATA - Binding Protein; TATA Binding Protein (TBP)

TATA binding protein; TATA-box-binding protein; CG9874 gene product from transcript CG9874-RA; TATA binding protein; CG9874-PA; Tbp-PA; TATA box binding protein; 42kDa polypeptide; TATA box-binding protein; TATA-binding protein; TATA-box binding protein; TATA binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; Transcription initiation factor TFIID TBP subunit

Tbp; Tbp; CG9874; DmelCG9874; dTbp; dTBP; dTFIID; RBP; TBP; TBP38; TfIID; TFIID; TFIIDtau; BTF1; TFIID

TBP_DROME

Monoclonal

IgG1

Mouse

353

Anti-TATA - Binding Protein [Murine MAb recognizes epitope within aa residues 1-20 of human, mouse and rat TBP.]. This antibody recognizes an epitope within amino acid residues 1-20 of human, mouse and rat TBP. It does not react with TBP from Drosophila, yeast, silk worm, or Xenopus. The specific epitope for this antibody is accessible when the C-terminal domain of TBP is removed or when TBP is complexed with DNA.

200 ug Protein G purified antibody in PBS, pH 7.4.

These antibodies are stable for at least one (1) year at -20 degree C to -70 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles

Western Blot, Immunoprecipitation

This antibody may be used in Western Blot and electrophoretic mobility (gel shift) assays to detect mammalian TBP. It may also be used to immunoprecipitate a truncated TBP molecule containing only the N-terminal domain.

Antigen: N-terminal domain of the human TATA-binding protein (TBP).

Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.

Protein Transcription Antibodies

17647997

NP_523805.1

NM_079081.3

P20227

38,451 Da

Basal Transcription Factors Pathway 3074!!Basal Transcription Factors Pathway 443!!Eukaryotic Transcription Initiation Pathway 198256!!Formation And Maturation Of MRNA Transcript Pathway 365767!!Gene Expression Pathway 365764!!RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway 365542!!RNA Polymerase II Pre-transcription Events Pathway 365534!!RNA Polymerase II Promoter Escape Pathway 365538!!RNA Polymerase II Transcription Pathway 365533!!RNA Polymerase II Transcription Initiation Pathway 365537

Function: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Ref.1 Ref.2 Ref.8. Subunit structure: Belongs to the TFIID complex which is composed of TATA binding protein (Tbp) and a number of TBP-associated factors (Tafs). Binds DNA as monomer. Interacts with TFIIA-L heterotrimer. Interacts with Taf1, Taf2, Taf5 and Taf12. Ref.8 Ref.9 Ref.10 Ref.11 Ref.12. Subcellular location: Nucleus. Sequence similarities: Belongs to the TBP family.

0.2 mg

340 USD