catalog number :
MBS190416
products full name :
SRC-1 Monoclonal Antibody
products short name :
SRC-1
products name syn :
Anti-SRC-1; SRC
other names :
SRC oncogene related family member (src-1); Protein tyrosine kinase; SRC oncogene related family member (src-1)
other gene names :
src-1; src-1
uniprot entry name :
Q8T6F8_CAEEL
specificity :
Anti-SRC-1 [Murine MAb recognizes an epitope within aa 477-947 of human SRC-1.]. This antibody recognizes human, monkey, mouse, and rat SRC-1.
form :
100 ug in 10 mM PBS, pH 7.4.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot, Immunoprecipitation
app notes :
Immunoblotting and Immunoprecipitation: use at 0.5-2 ug/ml. Positive control: COS cells
other info1 :
Antigen: Human SRC-1 (aa 477-947) gst-fusion protein.
other info2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Neuroscience and Signal Transduction Antibodies
products description :
SRC-1 (Steroid Receptor Coactivator- 1) is a member of a gene family that functions in the full transcriptional activation of the steroid hormone receptor superfamily and contains intrinsic histone acetyltransferase activitiy. The molecular weight of SRC- 1 is 160 kD, and it has a basic helixloop- helix-PAS domain.
ncbi acc num :
NP_490866.4
ncbi gb acc num :
NM_058465.4
ncbi mol weight :
60,661 Da
uniprot summary :
Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SAAS SAAS000980. Sequence similarities: Contains 1 SH2 domain. SAAS SAAS000980Contains 1 SH3 domain. RuleBase RU003338 SAAS SAAS000980Contains 1 protein kinase domain. SAAS SAAS000980