catalog number :
MBS190387
products full name :
Prolactin Monoclonal Antibody
products short name :
Prolactin
products name syn :
Anti-Prolactin; Prolactin
other names :
prolactin; Prolactin; prolactin; OTTHUMP00000017727; prolactin
other gene names :
PRL; PRL; PRL
uniprot entry name :
PRL_HUMAN
specificity :
Anti-Prolactin [Murine MAb recognizes human, rat, mouse, ovine, bovine, and squirrel monkey prolactin.]. This antibody recognizes prolactin of the following species: rat, human, mouse, ovine, bovine, and squirrel monkey. The epitope recognized by this antibody is restricted to a region that includes the carboxyl-terminal disulfide loop that is conserved among prolactins from several species. This antibody also completely inhibits the lactogenic activity of serum or purified prolactin from rat in the Nb2 lymphoma bioassay.
form :
100 ug Protein G-purified antibodyin PBS, pH 7.4.
storage stability :
These antibodies are stable for at least one (1) year at -20 degree C to -70 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.
tested application :
ELISA, Western Blot
app notes :
This antibody may be used in ELISA, Western Blot,and immunohisto-chemistry. Other applications are under investigation
other info1 :
Antigen: Sheep and human prolactin.
other info2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Hormone and Serum Protein Antibodies
products references :
Scammell et al. (1990) Molecular Cellular Endocrin 71: 125; Scammell et al. (1990) J Histochem Cytochem 38: 117; Scammell et al. (1992) Amer J Primatology 26: 35; Scammell et al. (1992) Endocrinol 131: 318; Scammell et al. (1992) Amer J Physiol 263: E520.
ncbi acc num :
CAA38264.1
ncbi mol weight :
25,876 Da
ncbi pathways :
Amyloids Pathway 366238!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!ErbB4 Signaling Events Pathway 137991!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Jak-STAT Signaling Pathway 83077!!Jak-STAT Signaling Pathway 488!!Neuroactive Ligand-receptor Interaction Pathway 83053!!Neuroactive Ligand-receptor Interaction Pathway 462!!Prostaglandin Synthesis And Regulation Pathway 198912
uniprot summary :
Function: Prolactin acts primarily on the mammary gland by promoting lactation. Subcellular location: Secreted. Sequence similarities: Belongs to the somatotropin/prolactin family. Sequence caution: The sequence CAA38264.1 differs from that shown. Reason: Frameshift at position 8.