catalog number :
MBS190300
products full name :
JAB-1 Monoclonal Antibody
products short name :
JAB-1
products name syn :
Anti-JAB-1; JAB-1
specificity :
Anti-JAB-1 [Murine MAb recognizes human and mouse JAB-1; epitope is within aa 1-334 of mouse JAB-1.]. This antibody recognizes human and mouse JAB-1
form :
100 ug in 10 mM PBS, pH 7.4.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
Immunoblot, Immunoprecipitation
app notes :
Immunoblotting and Immunoprecipitation: use at 0.5-1 ug/ml. Positive controls: 293 cells and recombinant fusion protein.
other info1 :
Antigen: Mouse JAB-1 gst-fusion protein (aa 1-334) expressed in E. coli.
other info2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Neuroscience and Signal Transduction Antibodies
products description :
JAB-1 is a 38 kD protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the "signalosome" which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants which plays an important role in light-mediated plant development. Although the specific function of JAB-1 is unclear, it appears to be involved in targeting proteins for degradation by the proteasome.