product summary
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company name :
MyBioSource
product type :
antibody
product name :
Interleukin-1 Receptor Monoclonal Antibody
catalog :
MBS190297
quantity :
0.2 mg
price :
320 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
ELISA, immunohistochemistry, radioimmunoassay
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS190297
products type :
Antibody
products full name :
Interleukin-1 Receptor Monoclonal Antibody
products short name :
Interleukin-1 receptor
products name syn :
Anti-Interleukin-1 receptor; Interleukin-1 Receptor
other names :
interleukin 1 receptor; Interleukin-1 receptor type 1; interleukin-1 receptor type 1; IL-1R-1; IL-1RT1; IL-1RT-1; antigen CD121a; OTTHUMP00000161344; OTTHUMP00000203887; OTTHUMP00000203888; OTTHUMP00000203889; OTTHUMP00000203891; OTTHUMP00000207977; interleukin receptor 1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family member A; interleukin 1 receptor alpha, type I; interleukin 1 receptor, type I; CD121 antigen-like family member A; Interleukin-1 receptor alpha; IL-1R-alpha; Interleukin-1 receptor type I; p80
other gene names :
IL1R1; IL1R1; P80; IL1R; IL1RA; CD121A; D2S1473; IL-1R-alpha; IL1R; IL1RA; IL1RT1
uniprot entry name :
IL1R1_HUMAN
clonality :
Monoclonal
isotype :
IgG2b
host :
Mouse
specificity :
Anti-Interleukin-1 receptor [Murine MAbs recognize human IL-1 receptor; no effect on IL-1 binding.]. These antibodies react with cell surface and soluble human IL-1 receptor; Specific epitopes are unknown, but they do partially inhibit (30-50%) binding of one another to IL-1 receptor. They do not block binding of IL-1 to receptor, and they do not cross-react with receptors for human IL-2 or IL-4.
form :
200 ug Protein G-purified antibody in PBS, pH 7.4
storage stability :
These antibodies are stable for at least one (1) year at -20 degree C to -70 degree C. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles
tested application :
ELISA, Radioimmunoassay, Immunohistochemistry
app notes :
ELISA: Can be used as capture reagents or second antibody at a concentration of 5 ug/ml. RIA: Concentrations of 20-30 ng/ml of these antibodies will bind radiolabeled IL-1 receptor in a radioimmunoassay format. Immunohistochemistry: IL-1 receptor can be detected on cultured cells using antibody concentrations of 10-100 ug/ml.
other info1 :
Antigen: The extracellular domain of the type I human IL-1 receptor (Genzyme Diagnostics).
other info2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Hormone and Serum Protein Antibodies
ncbi gi num :
307046
uniprot acc num :
P14778
ncbi mol weight :
65,402 Da
ncbi pathways :
Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Apoptosis Pathway 83060!!Apoptosis Pathway 470!!Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Hematopoietic Cell Lineage Pathway 83078
ncbi summary :
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq]
uniprot summary :
Function: Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2. Subunit structure: Binds IL1RAP. Subcellular location: Membrane; Single-pass type I membrane protein. Sequence similarities: Belongs to the interleukin-1 receptor family.Contains 3 Ig-like C2-type (immunoglobulin-like) domains.Contains 1 TIR domain.
size :
0.2 mg
price :
320 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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