product summary
request information :
company name :
MyBioSource
product type :
antibody
product name :
Human Neurotrophin-4 Monoclonal Antibody
catalog :
MBS190249
quantity :
0.5 mg
price :
380 USD
clonality :
monoclonal
host :
mouse
reactivity :
human
application :
ELISA
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS190249
products type :
Antibody
products full name :
Human Neurotrophin-4 Monoclonal Antibody
products short name :
Neurotrophin-4
products name syn :
Mouse Anti Human Neurotrophin-4; Neurotrophin-4
other names :
Neurotrophin 4; Neurotrophin-4; neurotrophin-4; NT-4; NT-5; neurotrophin-5; neutrophic factor 4; neurotrophic factor 4; neurotrophic factor 5; neurotrophin 5 (neurotrophin 4/5); neurotrophin 4; Neurotrophin-5; NT-5; Neutrophic factor 4
other gene names :
NTF4; NTF4; NT4; NT5; NTF5; GLC10; GLC1O; NT-4/5; NTF5
uniprot entry name :
NTF4_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
host :
Mouse
specificity :
Mouse Anti Human Neurotrophin-4 [Mouse monoclonal antibody to human Neurotrophin-4]
storage stability :
Store lyophilized product at 4 degree C. After reconstitution, aliquot and store at -20 degree C. Stable 2 years lyophilized; one month in solution at 4 degree C.
tested application :
ELISA
other info1 :
Antigen: recombinant human neurotrophin-4
other info2 :
Stabilizer: None. Preservatives: None. Dilutions Instructions: Reconstitute with water. Mix gently, washing the sides of the vial. Wait 1 minute before use.
products categories :
Growth Factors/Cytokines/Receptor Antibodies
ncbi gi num :
15214591
ncbi acc num :
AAH12421.1
uniprot acc num :
P34130
ncbi mol weight :
22,427 Da
ncbi pathways :
MAPK Signaling Pathway 198779!!MAPK Signaling Pathway 83048!!MAPK Signaling Pathway 456!!Neurotrophic Factor-mediated Trk Receptor Signaling Pathway 137977!!Neurotrophin Signaling Pathway 101143!!Neurotrophin Signaling Pathway 100064!!P75(NTR)-mediated Signaling Pathway 138019
ncbi summary :
This gene is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood. [provided by RefSeq]
uniprot summary :
Function: Target-derived survival factor for peripheral sensory sympathetic neurons. Subcellular location: Secreted. Tissue specificity: Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues. Involvement in disease: Defects in NTF4 may be associated with susceptibility to primary open angle glaucoma type 1O (GLC1O) [. MIM:613100]. A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. The disease is asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. Sequence similarities: Belongs to the NGF-beta family.
size :
0.5 mg
price :
380 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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