This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Estrogen Receptor- beta Monoclonal Antibody
catalog :
MBS190148
quantity :
0.1 ml
price :
420 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
rat
application :
western blot
product information
catalog number :
MBS190148
products type :
Antibody
products full name :
Estrogen Receptor- beta Monoclonal Antibody
products short name :
Estrogen Receptor beta
products name syn :
Anti-Estrogen Receptor beta; Estrogen Receptor-beta
other names :
estrogen receptor beta; Estrogen receptor 2 beta, isoform CRA_a; estrogen receptor beta; estrogen receptor 2 beta; nuclear receptor subfamily 3 group A member 2; estrogen receptor 2 (ER beta)
other gene names :
Esr2; Esr2; Erb2; ERbeta; ER-beta; ERb2
uniprot entry name :
Q59IV8_RAT
clonality :
Monoclonal
isotype :
IgG2b kappa
host :
Mouse
sequence length :
567
specificity :
Anti-Estrogen Receptor beta [Murine MAb to fusion protein corresponding to aa 1-153 of human estrogen receptor-beta, a member of the steroid family of nuclear receptors.]. This antibody recognizes human ER- beta , a novel receptor (approx. 52 kD) recently isolated from testis. The size and structure of ER- beta are very similar to ER- alpha with the ligand and DNA binding domains being highly conserved. The N-terminus of each receptor, which serves as their transactivation domain, are significantly different. Like ER- alpha , ER- beta binds to estrogen with a high affinity and regulates estrogen-specific gene activation through direct interaction with estrogen response elements
form :
100 ug Protein G-purified antibody in PBS, pH 7.4
storage stability :
This antibody is stable for at least one (1) year at -70 degree C. Avoid multiple freeze thaw cycles.
tested application :
Immunoblot
app notes :
Immunoblotting: use at 1-5 ug/ml. Positive controls: Native receptor from human thymus, spleen, ovary, and testisor recombinant protein.
other info1 :
Antigen: 6-His fusion protein containing the region encoding aa 1-153of human estrogen receptor- beta (ER- beta ) expressed in E. coli.
other info2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Cancer Research Products
ncbi gi num :
6978817
ncbi acc num :
NP_036886.1
ncbi gb acc num :
NM_012754.1
uniprot acc num :
Q59IV8
ncbi mol weight :
63,322 Da
ncbi pathways :
Androgen Receptor Signaling Pathway 198529!!Gene Expression Pathway 368173!!Generic Transcription Pathway 368174!!Nuclear Receptor Transcription Pathway 368176!!Nuclear Receptors Pathway 198498!!Ovarian Infertility Genes Pathway 198450
ncbi summary :
binds estrogen and mediates transcriptional activation [RGD]
uniprot summary :
Sequence similarities: Belongs to the nuclear hormone receptor family. RuleBase RU000377Contains 1 nuclear receptor DNA-binding domain. SAAS SAAS000536
size :
0.1 ml
price :
420 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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