catalog number :
MBS190146
products full name :
E-Selectin Monoclonal Antibody
products short name :
E-selectin
products name syn :
E-selectin
other names :
E-selectin; E-selectin; E-selectin; ELAM-1; OTTHUMP00000032745; OTTHUMP00000032746; OTTHUMP00000032747; OTTHUMP00000032748; OTTHUMP00000032749; endothelial adhesion molecule 1; CD62 antigen-like family member E; endothelial leukocyte adhesion molecule 1; leukocyte endothelial cell adhesion molecule 2; leukocyte-endothelial cell adhesion molecule 2; selectin E
other gene names :
SELE; ELAM; ESEL; CD62E; ELAM1; LECAM2
uniprot entry name :
Q6ULR7_HUMAN
specificity :
E-selectin [This mouse monoclonal antibody recognizes CD62E-positive cells.]. This antibody recognizes CD62Epositive cells. CD62E is the type 1 transmembrane glycoprotein also known as E-selectin or endothelialleukocyte adhesion molecule-1 (ELAM- 1). It is expressed on cytokinestimulated endothelial cells.
form :
100 ug Protein G-purified antibody in phosphate-buffered saline, pH 7.4.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
tested application :
ELISA, Flow Cytometry, Immunohistochemistry
app notes :
Flow cytometry: use at 0.5-1 ug/10^6 cells. Immunohistochemistry: use at 2-5 ug/ml. ELISA: use at 2-5 ug/ml.
other info1 :
Antigen: TNF-activated human umbilical endothelial cells.
other info2 :
Stabilizer: None. Preservatives: 0.1% sodium azide. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Cell Adhesion Molecule Antibodies
ncbi acc num :
AAQ67702.1
ncbi mol weight :
14,343 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway 138006!!African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Cell Adhesion Molecules (CAMs) Pathway 83069!!Cell Adhesion Molecules (CAMs) Pathway 480!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!Malaria Pathway 152665!!Malaria Pathway 152657!!Thromboxane A2 Receptor Signaling Pathway 138060
ncbi summary :
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq]