product summary
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company name :
MyBioSource
product type :
antibody
product name :
DNA Ligase I Monoclonal Antibody
catalog :
MBS190122
quantity :
0.1 ml
price :
420 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
product information
catalog number :
MBS190122
products type :
Antibody
products full name :
DNA Ligase I Monoclonal Antibody
products short name :
DNA Ligase I
products name syn :
Anti-DNA Ligase I; DNA Ligase I
other names :
DNA ligase I; DNA ligase 1; DNA ligase 1; polydeoxyribonucleotide synthase ATP 1; polydeoxyribonucleotide synthase [ATP] 1; ligase I, DNA, ATP-dependent; DNA ligase I; Polydeoxyribonucleotide synthase [ATP] 1
other gene names :
LIG1; LIG1; MGC117397; MGC130025
uniprot entry name :
DNLI1_HUMAN
clonality :
Monoclonal
isotype :
IgG1 kappa
host :
Mouse
sequence length :
919
specificity :
Anti-DNA Ligase I [Murine MAb recognizes human DNA Ligase I, a 125 kD ligase involved in joining of DNA strand breaks.]. This antibody recognizes human DNA Ligase I (125 kD), one of the four ligase proteins found in mammalian cells that are required for the joining of DNA strand breaks that occur during DNA replication, repair, and recombination.
form :
100 ug Protein G-purified antibody in PBS, pH 7.4
storage stability :
This antibody is stable for at least one (1) year at -70 degree C. Avoid multiple freeze thaw cycles.
tested application :
Immunoblot, Immunoprecipitation
app notes :
Immunoblotting: use at 1-5 ug/ml. Immunoprecipitation: use at 1-5 ug/ml. Positive controls: MCF-7 cells or recombinant protein.
other info1 :
Antigen: Recombinant human DNA Ligase I (aa 1-919) purified from baculovirus infected Sf9 cells.
other info2 :
Stabilizer: None. Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Cancer Research Products
ncbi gi num :
187143
ncbi acc num :
AAA59518.1
uniprot acc num :
P18858
ncbi mol weight :
101,736 Da
ncbi pathways :
Base Excision Repair Pathway 105838!!Base Excision Repair Pathway 83043!!Base Excision Repair Pathway 451!!Cell Cycle, Mitotic Pathway 105765!!Chromosome Maintenance Pathway 161048!!DNA Repair Pathway 105837!!DNA Replication Pathway 105897!!DNA Replication Pathway 83039!!DNA Replication Pathway 444!!DNA Strand Elongation Pathway 105789
ncbi summary :
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq]
uniprot summary :
Function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. Catalytic activity: ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). Cofactor: Magnesium. Ref.18. Subcellular location: Nucleus. Sequence similarities: Belongs to the ATP-dependent DNA ligase family.
size :
0.1 ml
price :
420 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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