catalog number :
MBS190071
products full name :
Bovine Osteocalcin Monoclonal Antibody
products short name :
Bovine Osteocalcin
products name syn :
Bovine Osteocalcin; Osteocalcin
other names :
osteocalcin preproprotein; Osteocalcin; osteocalcin; bone Gla protein; OTTHUMP00000016586; gamma-carboxyglutamic acid-containing protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); bone gamma-carboxyglutamate (gla) protein; Bone Gla protein; BGP; Gamma-carboxyglutamic acid-containing protein
other gene names :
BGLAP; BGLAP; OC; BGP
uniprot entry name :
OSTCN_HUMAN
specificity :
Bovine Osteocalcin [Mouse monoclonal antibody to Bovine Osteocalcin]. Epitope: Includes the gamma -carboxylated residue at position 17. Subclass: IgG2a : Reactivity: Bov, Hu, Rat, Rbt, Pig, Dog, Goat, Sheep, Chicken; none with Mouse.
form :
100 ug IgG in 10 mM PBS, pH 7.4, lyophilized.
storage stability :
Lyophilized antibody is stable at 4 degree C for 2 years. Store the reconstituted solution in aliquots at -20 degree C for one year or at 4 degree C for 6 months. Avoid repeated freeze-thaw cycles.
tested application :
ELISA, Western Blot, Immunohistochemistry
app notes :
Immunohistochemistry: 10 ug/ml on paraffin embedded and frozen tissue sections.
other info1 :
Antigen: Bovine osteocalcin
other info2 :
Stabilizer: 1% BSA . Preservatives: 0.1% Sodium Azide . Dilutions Instructions: Reconstitute in distilled water to the final desired concentration.
products categories :
Hormone and Serum Protein Antibodies
ncbi acc num :
NP_954642.1
ncbi gb acc num :
NM_199173.4
ncbi mol weight :
10,963 Da
ncbi pathways :
Cell Cycle, Mitotic Pathway 105765!!DNA Replication Pathway 105897!!FGF Signaling Pathway 137989!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!M Phase Pathway 105812!!Mitotic M-M/G1 Phases Pathway 160943!!Mitotic Prometaphase Pathway 105815!!Notch-mediated HES/HEY Network Pathway 169347!!Regulation Of Retinoblastoma Protein Pathway 137916!!Validated Transcriptional Targets Of AP1 Family Members Fra1 And Fra2 Pathway 169349
uniprot summary :
Function: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Subcellular location: Secreted. Post-translational modification: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. Sequence similarities: Belongs to the osteocalcin/matrix Gla protein family.Contains 1 Gla (gamma-carboxy-glutamate) domain.