product summary
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company name :
MyBioSource
product type :
antibody
product name :
Beta-Lactamase Monoclonal Antibody
catalog :
MBS190070
quantity :
0.1 mg
price :
205 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
[8A5.A10]
application :
western blot, ELISA
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS190070
products type :
Antibody
products full name :
Beta-Lactamase Monoclonal Antibody
products short name :
[beta lactamase]
products name syn :
[Anti-beta lactamase; Beta-Lactamase]
products gene name :
[BLA]
clonality :
Monoclonal
isotype :
IgG1
clone :
[8A5.A10]
host :
Mouse
sequence :
MSIQHFRVAL IPFFAAFCLP VFAHPETLVK VKDAEDQLGA RVGYIELDLN SGKILESFRP EERFPMMSTF KVLLCGAVLS RVDAGQEQLG RRIHYSQNDL VEYSPVTEKH LTDGMTVREL CSAAITMSDN TAANLLLTTI GGPKELTAFL HNMGDHVTRL DRWEPELNEA IPNDERDTTM PAAMATTLRK LLTGELLTLA SRQQLIDWME ADKVAGPLLR SALPAGWFIA DKSGAGERGS RGIIAALGPD GKPSRIVVIY TTGSQATMDE RNRQIAEIGA SLIKHW
specificity :
This antibody recognizes TEM-1-type beta-lactamases.
form :
Protein G-purified antibody in PBS, pH 7.4.
storage stability :
This product is stable for at least one (1) year at -20 degree C. Store in appropriate aliquots to avoid multiple freeze-thaw cycles.
tested application :
ELISA, Immunoblot
app notes :
Immunoblotting: use at 10ug/ml. Predicted molecular weight ~29kDa. ELISA: use at 10-20ug/ml (optimized for immobilized beta-lactamase at 10ug/ml). These are recommended concentrations. End users should determine optimal concentrations for their application.
other info1 :
Antigen: 5'-His-tagged E.coli 205 TEM-1 R+ beta-lactamase. Dilution Instruction: Dilute in PBS or medium that is identical to that used in the assay system.
products categories :
Infectious Disease Antibodies
products description :
The beta-lactam antibiotics (penicillins and cephalosporins) are the most frequently used antimicrobial agents. All of the beta-lactams are structurally related through the presence of a core beta-lactam ring. Bacterial resistance to beta-lactams continues to increase, primarily due to the production of betalactamases. Beta-lactamases catalyze the hydrolysis of the beta-lactam bond which destroys antibacterial activity. Bacteria that produce TEM- or SHVtype beta-lactamases have point mutations in structural genes that have extended the substrate specificity of these beta-lactamases. As a result, many of the beta-lactamase-producing Gram-negative pathogens have become multi-drug resistant.
uniprot acc num :
P62593
ncbi mol weight :
~29kDa
uniprot summary :
TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lactamase inhibitors.
size1 :
0.1 mg
price1 :
205 USD
size2 :
0.5 mg
price2 :
345
size3 :
1 mg
price3 :
645
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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