catalog number :
MBS190040
products full name :
Anti-Hsp70/Hsc70 Monoclonal Antibody
products short name :
Hsp70/Hsc70
products name syn :
Hsp70/Hsc70
specificity :
Hsp70/Hsc70 [Mouse monoclonal antibody to Hsp70/Hsc70]. This antibody detects 72 and 73 kDa proteins corresponding to the predicted molecular masses of Hsp70 and Hsc70, respectively, on immunoblots of human, mouse, rat, rabbit, monkey, hamster, guinea pig, dog, bovine, sheep, pig, chicken yeast, fish, and Xenopus samples. This antibody recognizes the inducible and constitutive forms of Hsp70 and does not cross-react with Hsp90.
form :
100ug in PBS, pH 7.4, purified by Protein G affinity chromatography.
storage stability :
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
tested application :
Immunoblot, Immunohistochemistry
app notes :
Immunoblotting: use at 1ug/ml. Immunohistochemistry: use at 5ug/ml. These are recommended concentrations. User should determine optimal concentrations for their application. Positive control: Canine MDCK cell lysate.
other info1 :
Antigen: Chicken Hsp70/Hsp90 complex.
other info2 :
Preservatives: None. Available on request. Dilutions Instructions: Dilute in PBS or medium which is identical to that used in the assay system.
products categories :
Heat Shock and Stress Proteins
products description :
Members of the Hsp70 family are molecular chaperones that function in protein folding, transport, maturation and degradation by binding to nascent polypeptide chains as well as partially folded protein intermediates and preventing their aggregation and misfolding. The 70 kDa heat shock cognate protein, Hsc70, is closely related biochemically and biologically to Hsp70.
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)